Antifungal resistance in dermatophytes: Recent trends and therapeutic implications

A Khurana, K Sardana, A Chowdhary - Fungal Genetics and Biology, 2019 - Elsevier
Dermatophytoses or tinea refers to superficial fungal infection of keratinized tissues.
Although generally considered easy to treat, recalcitrant infections, presenting as extensive …

Superficial Dermatophytosis across the World's Populations: Potential Benefits from Nanocarrier-Based Therapies and Rising Challenges

P Keshwania, N Kaur, J Chauhan, G Sharma… - ACS …, 2023 - ACS Publications
The most prevalent infection in the world is dermatophytosis, which is a major issue with
high recurrence and can affect the entire body including the skin, hair, and nails. The major …

Azole resistance in dermatophytes: prevalence and mechanism of action

M Ghannoum - Journal of the American Podiatric Medical …, 2016 - Am Podiatric Med Assoc
Azole antifungal agents (eg, fluconazole and itraconazole) have been widely used to treat
superficial fungal infections caused by dermatophytes and, unlike the allylamines (such as …

Treatment of onychomycosis in an era of antifungal resistance: role for antifungal stewardship and topical antifungal agents

AK Gupta, B Elewski, WS Joseph, SR Lipner… - Mycoses, 2024 - Wiley Online Library
A growing body of literature has marked the emergence and spread of antifungal resistance
among species of Trichophyton, the most prevalent cause of toenail and fingernail …

Newer topical treatments in skin and nail dermatophyte infections

K Sahni, S Singh, S Dogra - Indian dermatology online journal, 2018 - journals.lww.com
Dermatophytes are amongst the most common causative agents of fungal infections
worldwide and widespread in the developing countries. Various studies have found the …

Multi-drug resistant oral Candida species isolated from HIV-positive patients in South Africa and Cameroon

PM dos Santos Abrantes, CP McArthur… - … and infectious disease, 2014 - Elsevier
Candida species are a common cause of infection in immune-compromised HIV-positive
individuals, who are usually treated with the antifungal drug, fluconazole, in public hospitals …

Epidemiology, risk factors and antimicrobial profile of Vulvovaginal Candidiasis (VVC): A study among women in the central region of Saudi Arabia

D Venugopal, K Husain, SA Mustafa… - Journal of Medical …, 2021 - Elsevier
Background Candida spp. is a fungal resident of the normal microbiota of gastrointestinal
tract, reproductive mucosa and oral cavity. Hence, a majority of the healthy population may …

Major challenges in dermatophytosis treatment: current options and future visions

FHO AL-Khikani, AS Ayit - Egyptian Journal of Dermatology and …, 2021 - journals.lww.com
There is no part of the world can be cleared of the infection with dermatophytosis. Millions of
persons and animals around the world are infected with specialized filamentous fungi called …

The Susceptibility of Dermatophytes to Photodynamic Treatment with Special Focus on Trichophyton rubrum

TGM Smijs, S Pavel - Photochemistry and photobiology, 2011 - Wiley Online Library
Owing to the accessibility of skin to light, many applications of photodynamic treatment
(PDT) have been developed within dermatology. The recent increase of dermatological …

Trichophyton rubrum is Inhibited by Free and Nanoparticle Encapsulated Curcumin by Induction of Nitrosative Stress after Photodynamic Activation

LM Baltazar, AE Krausz, ACO Souza, BL Adler… - PloS one, 2015 - journals.plos.org
Antimicrobial photodynamic inhibition (aPI) utilizes radical stress generated from the
excitation of a photosensitizer (PS) with light to destroy pathogens. Its use against …