Neural stem cells as potential glioblastoma cells of origin
A Loras, LG Gonzalez-Bonet, JL Gutierrez-Arroyo… - Life, 2023 - mdpi.com
Glioblastoma multiforme (GBM) is the most malignant brain tumor in adults and it remains
incurable. These tumors are very heterogeneous, resistant to cytotoxic therapies, and they …
incurable. These tumors are very heterogeneous, resistant to cytotoxic therapies, and they …
[HTML][HTML] Intersecting pathways: the role of metabolic dysregulation, gastrointestinal microbiome, and inflammation in acute ischemic stroke pathogenesis and …
J Nuszkiewicz, B Kukulska-Pawluczuk, K Piec… - Journal of Clinical …, 2024 - mdpi.com
Acute ischemic stroke (AIS) remains a major cause of mortality and long-term disability
worldwide, driven by complex and multifaceted etiological factors. Metabolic dysregulation …
worldwide, driven by complex and multifaceted etiological factors. Metabolic dysregulation …
[HTML][HTML] Novel synergistic mechanism of 11-keto-β-boswellic acid and Z-Guggulsterone on ischemic stroke revealed by single-cell transcriptomics
T Liu, M Bai, M Liu, T Li, Y Liao, C Zhao, M Yao… - Pharmacological …, 2023 - Elsevier
Although strides have been made, the challenge of preventing and treating ischemic stroke
continues to persist globally. For thousands of years, the natural substances Frankincense …
continues to persist globally. For thousands of years, the natural substances Frankincense …
From inflammation to metastasis: The central role of miR-155 in modulating NF-κB in cancer
Cancer is a multifaceted, complex disease characterized by unchecked cell growth, genetic
mutations, and dysregulated signalling pathways. These factors eventually cause evasion of …
mutations, and dysregulated signalling pathways. These factors eventually cause evasion of …
In situ direct reprogramming of astrocytes to neurons via polypyrimidine tract-binding protein 1 knockdown in a mouse model of ischemic stroke
M Yuan, Y Tang, T Huang, L Ke… - Neural Regeneration …, 2024 - journals.lww.com
In situ direct reprogramming technology can directly convert endogenous glial cells into
functional neurons in vivo for central nervous system repair. Polypyrimidine tract-binding …
functional neurons in vivo for central nervous system repair. Polypyrimidine tract-binding …