The effect of local renin angiotensin system in the common types of cancer

M Almutlaq, AA Alamro, HS Alamri… - Frontiers in …, 2021 - frontiersin.org
The Renin Angiotensin System (RAS) is a hormonal system that is responsible for blood
pressure hemostasis and electrolyte balance. It is implicated in cancer hallmarks because it …

Heart failure pharmacotherapy and cancer: pathways and pre-clinical/clinical evidence

NV Sayour, ÁM Paál, P Ameri, WC Meijers… - European Heart …, 2024 - academic.oup.com
Heart failure (HF) patients have a significantly higher risk of new-onset cancer and cancer-
associated mortality, compared to subjects free of HF. While both the prevention and …

NCK1 promotes the angiogenesis of cervical squamous carcinoma via Rac1/PAK1/MMP2 signal pathway

P Xia, M Huang, Y Zhang, X Xiong, M Yan, X Xiong… - Gynecologic …, 2019 - Elsevier
Objective The study was to explore the roles of Nck1 in the angiogenesis of cervical
squamous cell carcinoma (CSCC). Methods mRNA and protein levels were evaluated with …

Field carcinogenesis for risk stratification of colorectal cancer

D Rebello, E Rebello, M Custodio, X Xu… - Advances in Cancer …, 2021 - Elsevier
Colorectal cancer (CRC) is characterized by genetic-environmental interplay leading to
diffuse changes in the entire colonic mucosa (field carcinogenesis or field of injury) and to a …

Losartan and vitamin D inhibit colonic tumor development in a conditional Apc-deleted mouse model of sporadic colon cancer

U Dougherty, R Mustafi, HI Haider, A Khalil… - Cancer Prevention …, 2019 - AACR
Colorectal cancer is a leading cause of cancer deaths. The renin-angiotensin system (RAS)
is upregulated in colorectal cancer, and epidemiologic studies suggest RAS inhibitors …

Renin Angiotensin System Activity in Different Cancers: Mechanistic Insight and Preclinical Studies

A Singh, PMS Bedi - The Renin Angiotensin System in Cancer, Lung …, 2023 - Springer
Abstract The Renin Angiotensin System (RAS) is maintain arterial blood pressure as well as
fluid and electrolyte balance in human body. In recent there decades, it has been emerged …