The changes in intracellular free calcium (Ca2+) levels are one of the most widely regulators
of cell function; therefore, calcium as a universal intracellular mediator is involved in very …

Exocrine pancreas has been the field of many successful studies in pancreatic physiology
and pathology. However, related disease-acute pancreatitis (AP) is still takes it toll with more …

Patients with recurrent acute pancreatitis (RAP) are at significant risk of developing early
chronic pancreatitis (CP), which progresses into irreversible, end-stage CP with severe …

Application of antioxidant enzymes in medical or industrial processes is limited due to their
high sensitivity to environmental conditions. Incorporation of such enzymes in …

With the explosion research on the gut microbiome in the recent years, much insight has
been accumulated in comprehending the crosstalk between the gut microbiota community …

Acute pancreatitis is initiated within pancreatic exocrine cells and sustained by dysregulated
systemic inflammatory responses mediated by neutrophils. Store-operated Ca2+ entry …

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Although severe abdominal pain is the main symptom of acute pancreatitis, its mechanisms
are poorly understood. An emerging body of literature evidence indicates that neurogenic …

Background and aims Thiopurine-induced acute pancreatitis (TIP) is one of the most
common adverse events among inflammatory bowel disease patients treated with …

Acute pancreatitis (AP) is one of the most common gastrointestinal tract diseases with
significant morbidity and mortality. Current treatments remain unspecific and supportive due …