[HTML][HTML] Novel tools to study cell-ECM interactions, cell adhesion dynamics and migration
Integrin-mediated cell adhesion is essential for cell migration, mechanotransduction and
tissue integrity. In vivo, these processes are regulated by complex physicochemical signals …
tissue integrity. In vivo, these processes are regulated by complex physicochemical signals …
[HTML][HTML] Osteocyte β3 integrin promotes bone mass accrual and force-induced bone formation in mice
L Qin, Z Chen, D Yang, T He, Z Xu, P Zhang… - Journal of Orthopaedic …, 2023 - Elsevier
Background Cell culture studies demonstrate the importance of β3 integrin in osteocyte
mechanotransduction. However, the in vivo roles of osteocyte β3 integrin in the regulation of …
mechanotransduction. However, the in vivo roles of osteocyte β3 integrin in the regulation of …
[HTML][HTML] Bioactive prosthesis interface compositing variable-stiffness hydrogels regulates stem cells fates to facilitate osseointegration through mechanotransduction
Z Wang, Y Zhao, H Bai, F Chang, X Yang… - International Journal of …, 2024 - Elsevier
Fluid hydrogel is proper to be incorporated with rigid porous prosthesis interface, acting as a
soft carrier to support cells and therapeutic factors, to enhance osseointegration. In the …
soft carrier to support cells and therapeutic factors, to enhance osseointegration. In the …
[HTML][HTML] Nano-clusters of ligand-activated integrins organize immobile, signalling active, nano-clusters of phosphorylated FAK required for mechanosignaling in focal …
Transmembrane signalling receptors, such as integrins, organise as nanoclusters that are
thought to provide several advantages including, increasing avidity, sensitivity (increasing …
thought to provide several advantages including, increasing avidity, sensitivity (increasing …
Three-dimensional multi-target super-resolution microscopy of cells using Metal-Induced Energy Transfer and DNA-PAINT
DNA-points accumulation for imaging in nanoscale topography (DNA-PAINT) is a potent
variant of single-molecule localization microscopy (SMLM) which is highly effective for …
variant of single-molecule localization microscopy (SMLM) which is highly effective for …
[HTML][HTML] New tools to study the interaction between integrins and latent TGFβ1
M Bachmann, J Kessler, E Burri, B Wehrle-Haller - bioRxiv, 2023 - ncbi.nlm.nih.gov
Transforming growth factor beta (TGFβ) 1 regulates cell differentiation and proliferation in
different physiological settings, but is also involved in fibrotic progression and protects …
different physiological settings, but is also involved in fibrotic progression and protects …
Heterospecific developmental models highlight the role of FBXO32 in neural crest lineages and the significance of its variant in pediatric melanoma
V Alexandra, G Clémence, G Tatiana, C Sophie - bioRxiv, 2023 - biorxiv.org
Melanoma is a rare sporadic pediatric cancer caused by de novo genetic accidents. To
analyze the involvement of FBXO32 of unknown biological significance, we set up original …
analyze the involvement of FBXO32 of unknown biological significance, we set up original …