[HTML][HTML] Predicting the effects of rare genetic variants on oncogenic signaling pathways: A computational analysis of HRAS protein function
The HRAS gene plays a crucial role in regulating essential cellular processes for life, and
this gene's misregulation is linked to the development of various types of cancers …
this gene's misregulation is linked to the development of various types of cancers …
OmeSim: a genetics-based nonlinear simulator for in-between-ome and phenotype
Z Long, Q Zhang - bioRxiv, 2024 - biorxiv.org
Motivation: Deciphering genetic basis of complex traits via genotype-phenotype association
stud-ies is a long-standing theme in genetics. The availability of molecular omics data (such …
stud-ies is a long-standing theme in genetics. The availability of molecular omics data (such …
Multivariate genome-wide association analysis by iterative hard thresholding
Motivation In a genome-wide association study, analyzing multiple correlated traits
simultaneously is potentially superior to analyzing the traits one by one. Standard methods …
simultaneously is potentially superior to analyzing the traits one by one. Standard methods …
[PDF][PDF] Multivariate Genomewide Association Analysis with IHT
2Department of Biostatistics, Fielding School of Public Health at UCLA, Los Angeles, USA
3Division of Epidemiology and Biostatistics, University of Arizona, USA 4Department of …
3Division of Epidemiology and Biostatistics, University of Arizona, USA 4Department of …
[图书][B] Scalable Algorithms for Genetic Association Studies, Genotype Imputation, and Ancestry Inference
BB Chu - 2021 - search.proquest.com
This dissertation develops statistical and computational methods for human genetics. We
consider problems in genome-wide association studies, imputation, phasing, and ancestry …
consider problems in genome-wide association studies, imputation, phasing, and ancestry …
[图书][B] Statistical Methods for Multivariate Genetic Analysis
SM Ji - 2022 - search.proquest.com
This dissertation develops statistical and computational methods for human genetics. We
consider modern solutions to estimate the power of proposed genetic studies, and propose …
consider modern solutions to estimate the power of proposed genetic studies, and propose …