Tissue-engineered decellularized extracellular matrix (ECM) scaffolds hold great potential to
address the donor shortage as well as immunologic rejection attributed to cells in …

Decellularized materials (DMs) are attracting more and more attention because of their
native structures, comparatively high bioactivity, low immunogenicity and good …

Transplantation is the only curative treatment option available for patients suffering from end‐
stage organ failure, improving their quality of life and long‐term survival. However, because …

Seriously compromised function of some organs can only be restored by transplantation.
Due to the shortage of human donors, the need to find another source of organs is of primary …

Decellularized extracellular matrix scaffold, widely utilized for organ engineering, often
undergoes matrix decomposition after transplantation and produces byproducts that cause …

Decellularization of tissues and organs has recently become a promising approach in tissue
engineering and regenerative medicine to circumvent the challenges of organ donation and …

The substantially growing gap between suitable donors and patients waiting for new organ
transplantation has compelled tissue engineers to look for suitable patient-specific …

A promising paradigm to regenerative medicine involves the application of biomaterials,
which makes a spurt of progress in the past 20 years. Of various biomaterials, decellularized …

Liver transplantation is currently the only effective treatment for patients with end-stage liver
disease; however, donor liver scarcity is a notable concern. As a result, extensive endeavors …

Various modifications have been performed on biomaterials to improve their applications in
tissue engineering and regenerative medicine. However, the challenges of immunogenicity …