[HTML][HTML] Recent advances and clinical translation of liposomal delivery systems in cancer therapy
J Chen, S Hu, M Sun, J Shi, H Zhang, H Yu… - European Journal of …, 2024 - Elsevier
The limitations of conventional cancer treatment are driving the emergence and
development of nanomedicines. Research in liposomal nanomedicine for cancer therapy is …
development of nanomedicines. Research in liposomal nanomedicine for cancer therapy is …
Advancement in design of nanostructured lipid carriers for cancer targeting and theranostic application
Background Cancer development is associated with abnormal, uncontrolled cell growth and
causes significant economic and social burdens to society. The global statistics of different …
causes significant economic and social burdens to society. The global statistics of different …
Chitosan nanoparticles as a smart nanocarrier for gefitinib for tackling lung cancer: Design of experiment and in vitro cytotoxicity study
Due to its poor solubility and systemic side effects, gefitinib (Gef) has limited application in
treatment of lung cancer. In this study, we used design of experiment (DOE) tools to gain the …
treatment of lung cancer. In this study, we used design of experiment (DOE) tools to gain the …
[HTML][HTML] PEGylated SLN as a promising approach for lymphatic delivery of gefitinib to lung cancer
Purpose The present study aimed to develop gefitinib-loaded solid lipid nanoparticles (GEF-
SLN), and GEF-loaded PEGylated SLN (GEF-P-SLN) for targeting metastatic lung cancer …
SLN), and GEF-loaded PEGylated SLN (GEF-P-SLN) for targeting metastatic lung cancer …
Gefitinib: an updated review of its role in the cancer management, its nanotechnological interventions, recent patents and clinical trials
Background: Gefitinib, a tyrosine kinase inhibitor, is effectively used in the targeted treatment
of malignant conditions. It suppresses the signal transduction cascades leading to cell …
of malignant conditions. It suppresses the signal transduction cascades leading to cell …
Surface-modified biobased polymeric nanoparticles for dual delivery of doxorubicin and gefitinib in glioma cell lines
Glioma is a malignant form of brain cancer that is challenging to treat due to the progressive
growth of glial cells. To target overexpressed folate receptors in glioma brain tumors, we …
growth of glial cells. To target overexpressed folate receptors in glioma brain tumors, we …
[HTML][HTML] Light-responsive micelles loaded with doxorubicin for osteosarcoma suppression
J Chen, C Qian, P Ren, H Yu, X Kong… - Frontiers in …, 2021 - frontiersin.org
The enhancement of tumor targeting and cellular uptake of drugs are significant factors in
maximizing anticancer therapy and minimizing the side effects of chemotherapeutic drugs. A …
maximizing anticancer therapy and minimizing the side effects of chemotherapeutic drugs. A …
[HTML][HTML] Hepatoprotective effect of curcumin nano-lipid carrier against cypermethrin toxicity by countering the oxidative, inflammatory, and apoptotic changes in wistar …
This study investigated the potential hepatoprotective activity of curcumin-incorporated nano-
lipid carrier (Cur-NLC) against cypermethrin (Cyp) toxicity in adult Wistar male rats. All …
lipid carrier (Cur-NLC) against cypermethrin (Cyp) toxicity in adult Wistar male rats. All …
Nanomedicines enhance minimally invasive therapy of pancreatic cancer
Pancreatic carcinoma (PCa) is a malignant tumor that is highly lethal and lacks an effective
treatment. Although surgical treatment, chemotherapy, and radiotherapy of PCa have …
treatment. Although surgical treatment, chemotherapy, and radiotherapy of PCa have …
[HTML][HTML] Engineered nanoscale lipid-based formulation as potential enhancer of gefitinib lymphatic delivery: cytotoxicity and apoptotic studies against the A549 cell …
The present study aimed to engineer a nanoscale lipid-based lymphatic drug delivery
system with D-α-Tocopherol polyethylene glycol 1000 succinate to combat the lymphatic …
system with D-α-Tocopherol polyethylene glycol 1000 succinate to combat the lymphatic …