Dendritic cells in cancer immunology

TL Murphy, KM Murphy - Cellular & molecular immunology, 2022 - nature.com
The clinical success of immune checkpoint therapy (ICT) has produced explosive growth in
tumor immunology research because ICT was discovered through basic studies of immune …

Genetic models of human and mouse dendritic cell development and function

DA Anderson III, CA Dutertre, F Ginhoux… - Nature Reviews …, 2021 - nature.com
Dendritic cells (DCs) develop in the bone marrow from haematopoietic progenitors that have
numerous shared characteristics between mice and humans. Human counterparts of mouse …

Dendritic cells revisited

M Cabeza-Cabrerizo, A Cardoso… - Annual review of …, 2021 - annualreviews.org
Dendritic cells (DCs) possess the ability to integrate information about their environment and
communicate it to other leukocytes, shaping adaptive and innate immunity. Over the years, a …

Estrogen receptor signaling in the immune system

B Chakraborty, J Byemerwa, T Krebs, F Lim… - Endocrine …, 2023 - academic.oup.com
The immune system functions in a sexually dimorphic manner, with females exhibiting more
robust immune responses than males. However, how female sex hormones affect immune …

Monocytes, macrophages, dendritic cells and neutrophils: an update on lifespan kinetics in health and disease

AA Patel, F Ginhoux, S Yona - Immunology, 2021 - Wiley Online Library
Phagocytes form a family of immune cells that play a crucial role in tissue maintenance and
help orchestrate the immune response. This family of cells can be separated by their nuclear …

Dendritic cells, monocytes and macrophages: a unified nomenclature based on ontogeny

M Guilliams, F Ginhoux, C Jakubzick, SH Naik… - Nature Reviews …, 2014 - nature.com
The mononuclear phagocyte system (MPS) has historically been categorized into
monocytes, dendritic cells and macrophages on the basis of functional and phenotypical …

GM-CSF mouse bone marrow cultures comprise a heterogeneous population of CD11c+ MHCII+ macrophages and dendritic cells

J Helft, J Böttcher, P Chakravarty, S Zelenay, J Huotari… - Immunity, 2015 - cell.com
Dendritic cells (DCs) are key players in the immune system. Much of their biology has been
elucidated via culture systems in which hematopoietic precursors differentiate into DCs …

[HTML][HTML] Development and function of dendritic cell subsets

A Mildner, S Jung - Immunity, 2014 - cell.com
Classical dendritic cells (cDCs) form a critical interface between innate and adaptive
immunity. As myeloid immune cell sentinels, cDCs are specialized in the sensing of …

Unsupervised high-dimensional analysis aligns dendritic cells across tissues and species

M Guilliams, CA Dutertre, CL Scott, N McGovern… - Immunity, 2016 - cell.com
Dendritic cells (DCs) are professional antigen-presenting cells that hold great therapeutic
potential. Multiple DC subsets have been described, and it remains challenging to align …

The development and function of lung-resident macrophages and dendritic cells

M Kopf, C Schneider, SP Nobs - Nature immunology, 2015 - nature.com
Gas exchange is the vital function of the lungs. It occurs in the alveoli, where oxygen and
carbon dioxide diffuse across the alveolar epithelium and the capillary endothelium …