The metabolic syndrome, a human disease

M Alemany - International journal of molecular sciences, 2024 - mdpi.com
This review focuses on the question of metabolic syndrome (MS) being a complex, but
essentially monophyletic, galaxy of associated diseases/disorders, or just a syndrome of …

Deletion of Rab GAP AS160 modifies glucose uptake and GLUT4 translocation in primary skeletal muscles and adipocytes and impairs glucose homeostasis

MN Lansey, NN Walker, SR Hargett… - American Journal …, 2012 - journals.physiology.org
Tight control of glucose uptake in skeletal muscles and adipocytes is crucial to glucose
homeostasis and is mediated by regulating glucose transporter GLUT4 subcellular …

Resveratrol improves glycemic control in insulin-treated diabetic rats: participation of the hepatic territory

CY Yonamine, E Pinheiro-Machado, ML Michalani… - Nutrition & …, 2016 - Springer
Background Resveratrol is a natural polyphenol that has been proposed to improve
glycemic control in diabetes, by mechanisms that involve improvement in insulin secretion …

Estradiol-induced regulation of GLUT4 in 3T3-L1 cells: involvement of ESR1 and AKT activation

RS Campello, LA Fátima… - Journal of …, 2017 - jme.bioscientifica.com
Impaired insulin-stimulated glucose uptake involves reduced expression of the GLUT4
(solute carrier family 2 facilitated glucose transporter member 4, SLC2A4 gene). 17β …

Beta hydroxy beta methylbutyrate supplementation impairs peripheral insulin sensitivity in healthy sedentary Wistar rats

CY Yonamine, SS Teixeira, RS Campello… - Acta …, 2014 - Wiley Online Library
Aim Investigate, in healthy sedentary rats, the potential mechanisms involved on the effects
of beta hydroxy beta methylbutyrate (HMB) supplementation upon the glycaemic …

[HTML][HTML] Aerobic Exercise Training Protects Against Insulin Resistance, Despite Low-Sodium Diet-Induced Increased Inflammation and Visceral Adiposity

V Del Bianco, GS Ferreira, APG Bochi… - International Journal of …, 2024 - mdpi.com
Dietary sodium restriction increases plasma triglycerides (TG) and total cholesterol (TC)
concentrations as well as causing insulin resistance and stimulation of the renin-angiotensin …

Insulin acutely triggers transcription of Slc2a4 gene: participation of the AT-rich, E-box and NFKB-binding sites

PA Moraes, CY Yonamine, DCP Junior, JVDC Esteves… - Life sciences, 2014 - Elsevier
Aims The insulin-sensitive glucose transporter protein GLUT4 (solute carrier family 2
member 4 (Slc2a4) gene) plays a key role in glycemic homeostasis. Decreased GLUT4 …

Recovery of insulin sensitivity and Slc2a4 mRNA expression depend on T3 hormone during refeeding

MM Zanquetta, AB Alves-Wagner, RC Mori… - Metabolism, 2014 - Elsevier
Objective GLUT4 protein, encoded by the Slc2a4 gene, plays a key role in muscle glucose
uptake, and its expression decreases in muscles under insulin resistance. Slc2a4/GLUT4 …

Expressions of hepatic genes, especially IGF-binding protein-1, correlating with serum corticosterone in microarray analysis

RY Cheng, LA Birely, NL Lum… - Journal of …, 2004 - jme.bioscientifica.com
Impaired insulin-stimulated glucose uptake involves reduced expression of the GLUT4
(solute carrier family 2 facilitated glucose transporter member 4, SLC2A4 gene). 17β …

耐力训练和适量限食轻度上调大鼠骨骼肌ER 分子伴侣表达并改善糖代谢的研究

胥靓, 伊木清, 楼望, 李伟军, 周丽丽, 许葆华… - 成都体育学院 …, 2014 - cdtyxb.cdsu.edu.cn
目的研究耐力训练和适量限食对骨骼肌内质网(endoplasmic reticulum, ER)
分子伴侣表达及糖代谢改善的影响. 方法37 只SD 大鼠分为安静组(S), 限食安静组(DS) …