Breast cancer is the most common cancer among women globally. Genomic instability (GI)
refers to the increased tendency to accrue genomic alterations. It drives heterogeneity and is …

Targeting the mitotic machinery using anti-mitotic drugs for elimination of cancer cells is a
century-old concept, which continues to be routinely used as a first line of treatment in the …

Background: Pancreatic cancer is highly lethal and aggressive with increasing trend of
mortality in both genders. An effective prediction model is needed to assess prognosis of …

Background Deregulation of microtubules and centrosome integrity is response for the
initiation and progression of human cancers. Sperm-associated antigen 5 (SPAG5) is …

Objective This study aims to explore whether miR-195-5p can inhibit proliferation and
induce apoptosis of non-small cell lung cancer (NSCLC) cells by targeting CEP55. Methods …

Background Bladder cancer is a malignant tumor in the urinary system with high mortality
and recurrence rates. However, the causes and recurrence mechanism of bladder cancer …

The centrosomal protein, CEP 55, is a key regulator of cytokinesis, and its overexpression is
linked to genomic instability, a hallmark of cancer. However, the mechanism by which it …

Human clear cell renal cell carcinoma (ccRCC) is one of the most common types of
malignant adult kidney tumors. We constructed a weighted gene co-expression network to …

This study aims to lay a foundation for studying the regulation of microRNAs (miRNAs) in
colon cancer by applying bioinformatics methods to identify miRNAs and their potential …

Background Hepatocellular carcinoma (HCC) is an extremely common malignant tumor with
worldwide prevalence. The aim of this study was to identify potential prognostic genes and …