Microalgae are microorganisms capable of producing bioactive compounds using
photosynthesis. Microalgae contain a variety of high value-added natural pigments such as …

Na+/H+ exchangers play pivotal roles in the control of cell and tissue pH by mediating the
electroneutral exchange of Na+ and H+ across cellular membranes. They belong to an …

All life forms defend their genome against DNA invasion. Eukaryotic cells recognize
incoming DNA and limit its transcription through repressive chromatin modifications. The …

A picture is beginning to emerge from a variety of organisms that for a subset of genes, the
most important sequences that regulate expression are situated not in the promoter but …

The recent discovery of the mode of action of the CRISPR/Cas9 system has provided
biologists with a useful tool for generating site-specific mutations in genes of interest. In …

Pre-mRNA processing steps are tightly coordinated with transcription in many organisms. To
determine how co-transcriptional splicing is integrated with transcription elongation and 3 …

Dravet syndrome (DS) is a developmental and epileptic encephalopathy caused by
monoallelic loss-of-function variants in the SCN1A gene. SCN1A encodes for the alpha …

A high prevalence of vitamin D (calcidiol) serum deficiency has been described in several
autoimmune diseases, including multiple sclerosis (MS), rheumatoid arthritis (AR), and …

The ability of plant somatic cells to dedifferentiate, form somatic embryos and regenerate
whole plants in vitro has been harnessed for both clonal propagation and as a key …

Efficient nuclear transgene expression in the green microalga Chlamydomonas reinhardtii is
generally hindered by low transcription rates. Introns can increase transcript abundance by …