Necrotizing fasciitis (NF) is a severe, rare, potentially lethal soft tissue infection that develops
in the scrotum and perineum, the abdominal wall, or the extremities. The infection …

534 Hypertension September 2016 vasodilation is unrelated to the tissue kallikrein–kinin
system. 18 In addition, kallistatin transgenic mice were found to have significantly lower …

Kallistatin, an endogenous plasma protein, exhibits pleiotropic properties in inhibiting
inflammation, oxidative stress and apoptosis, as evidenced in various animal models and …

Exudative age-related macular degeneration (AMD) is characterized by molecular
mechanisms responsible for the initiation of choroidal neovascularization (CNV) …

Curcumin is a natural product widely used due to its pharmacological effects. Nevertheless,
only a limited number of studies concerning the effects of curcumin on exudative age‑related …

The principle of hydrodynamic delivery was initially used to develop a method for the
delivery of plasmids into mouse hepatocytes through tail vein injection and has been …

Background The wingless-type MMTV integration site (Wnt) signaling is a group of signal
transduction pathways. In canonical Wnt pathway, Wnt ligands bind to low-density …

Abstract Group A Streptococcus (GAS) is a Gram‐positive bacterial pathogen that causes
significant morbidity and mortality worldwide. Recent clinical evidence suggests that the …

Kallistatin, a plasma protein, has been shown to exert multi‐factorial functions including
inhibition of inflammation, oxidative stress and apoptosis in animal models and cultured …

Introduction Kallistatin levels in the circulation are reduced in patients with sepsis and liver
disease. Transgenic mice expressing kallistatin are resistant to lipopolysaccharide (LPS) …