Mitochondria are a major target in hypoxic/ischemic injury. Mitochondrial impairment
increases with age leading to dysregulation of molecular pathways linked to mitochondria …

Hydrogen sulfide (H 2 S) is the most recent endogenous gasotransmitter that has been
reported to serve many physiological and pathological functions in different tissues. Studies …

Significance: An abundance of experimental evidence suggests that hydrogen sulfide (H2S)
plays a prominent role in physiology and pathophysiology. Many targets exist for H2S …

Ischemia‐reperfusion (I/R) injury is one of the major causes of high morbidity, disability, and
mortality in the world. I/R injury remains a complicated and unresolved situation in clinical …

Gaseous molecules have been increasingly explored for therapeutic development. Here,
following an analytical background introduction, a systematic review of medical gas …

In acute neuronal insult events, such as stroke, traumatic brain injury, and spinal cord injury,
pathological processes of secondary neuronal injury play a key role in the severity of insult …

Animals live in habitats fraught with a range of environmental challenges to their bodies and
brains. Accordingly, cells and organ systems have evolved stress-responsive signaling …

Recently, myriad studies have defined the versatile abilities of gasotransmitters and their
synthesizing enzymes to play a “Maestro” role in orchestrating several oncological and non …

The ability to detect oxygen availability is a ubiquitous attribute of aerobic organisms.
However, the mechanism (s) that transduce oxygen concentration or availability into …

Abstract Hydrogen sulfide (H 2 S), an endogenous gaseous mediator, has been shown to
have protective effects against neuronal damage caused by brain ischemia. In this study, we …