Paving the path toward multi-omics approaches in the diagnostic challenges faced in thyroid pathology

I Piga, V L'Imperio, G Capitoli, V Denti… - Expert Review of …, 2023 - Taylor & Francis
Introduction Despite advancements in diagnostic methods, the classification of
indeterminate thyroid nodules still poses diagnostic challenges not only in pre-surgical …

The journey towards clinical adoption of MALDI‐MS‐based imaging proteomics: from current challenges to future expectations

I Piga, F Magni, A Smith - FEBS letters, 2024 - Wiley Online Library
Among the spatial omics techniques available, mass spectrometry imaging (MSI) represents
one of the most promising owing to its capability to map the distribution of hundreds of …

[HTML][HTML] Unsupervised neural networks as a support tool for pathology diagnosis in MALDI-MSI experiments: A case study on thyroid biopsies

MS Nobile, G Capitoli, V Sowirono, F Clerici… - Expert Systems with …, 2023 - Elsevier
Artificial intelligence is getting a foothold in medicine for disease screening and diagnosis.
While typical machine learning methods require large labeled datasets for training and …

Cytomolecular classification of thyroid nodules using fine-needle washes aspiration biopsies

G Capitoli, I Piga, V L'Imperio, F Clerici, D Leni… - International Journal of …, 2022 - mdpi.com
Fine-needle aspiration biopsies (FNA) represent the gold standard to exclude the malignant
nature of thyroid nodules. After cytomorphology, 20–30% of cases are deemed …

Spatially Resolved Molecular Approaches for the Characterisation of Non-Invasive Follicular Tumours with Papillary-like Features (NIFTPs)

I Piga, V L'Imperio, L Principi, C Bellevicine… - International Journal of …, 2023 - mdpi.com
Noninvasive follicular thyroid neoplasms with papillary-like nuclear features (NIFTP) are low-
risk thyroid lesions most often characterised by RAS-type mutations. The histological …

[HTML][HTML] 空间组学技术在头颈部肿瘤个体化诊疗中的研究进展

徐晨阳, 王寅, 魏东敏, 李文明, 钱晔… - Journal of Clinical …, 2023 - ncbi.nlm.nih.gov
空间组学是继单细胞测序技术之后的另一个生物技术研究热点, 其能够弥补单细胞测序技术
无法获取细胞空间分布信息的缺陷。 空间组学主要研究细胞在组织样品中的相对位置关系 …

Advances of spatial omics in the individualized diagnosis and treatment of head and neck cancer

C Xu, Y Wang, D Wei, W Li, Y Qian, X Pan… - … er bi yan hou tou Jing …, 2023 - europepmc.org
空间组学是继单细胞测序技术之后的另一个生物技术研究热点, 其能够弥补单细胞测序技术无法
获取细胞空间分布信息的缺陷. 空间组学主要研究细胞在组织样品中的相对位置关系 …

[引用][C] Proteomics and its application in endocrine disorders.

SS Thakur - Biochimica et biophysica acta. Proteins and proteomics, 2021 - europepmc.org
Proteomics and its application in endocrine disorders. - Abstract - Europe PMC Sign in | Create
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