Inbreeding depression, the reduction of fitness caused by inbreeding, is a nearly universal
phenomenon that depends on past mutation, selection, and genetic drift. Recent estimates …

Restoring gene flow into small, isolated populations can alleviate genetic load and decrease
extinction risk (ie, genetic rescue), yet gene flow is rarely augmented as a conservation …

The unprecedented rate of extinction calls for efficient use of genetics to help conserve
biodiversity. Several recent genomic and simulation-based studies have argued that the …

The current rate of species extinction is rapidly approaching unprecedented highs, and life
on Earth presently faces a sixth mass extinction event driven by anthropogenic activity …

In recent years, scientists have realized that evolution can occur on timescales much shorter
than the" long lapse of ages" emphasized by Darwin—in fact, evolutionary change is …

Many species have fragmented distribution with small isolated populations suffering
inbreeding depression and/or reduced ability to evolve. Without gene flow from another …

Genetic rescue can increase the fitness of small, imperiled populations via immigration. A
suite of studies from the past decade highlights the value of genetic rescue in increasing …

Gene flow among populations can enhance local adaptation if it introduces new genetic
variants available for selection, but strong gene flow can also stall adaptation by swamping …

Whether inbreeding affects the demography and persistence of natural populations has
been questioned. However, new pedigree data from field populations and molecular and …

Translocations are being increasingly proposed as a way of conserving biodiversity,
particularly in the management of threatened and keystone species, with the aims of …