Traditionally, the development of a new solid dosage form is formulation-driven and less
focus is put on the design of a specific microstructure for the drug delivery system. However …

Extracellular vesicles (EVs) are small membraned vesicles and approximately 50–150 nm in
diameter. Almost all of the type of cells releases the EVs and circulates in the body fluids …

Millions of people worldwide are bilaterally blind due to corneal diseases including
infectious etiologies, trauma, and chemical injuries. While corneal transplantation can …

Inflammation that is not resolved in due course becomes a chronic disease. The treatment of
chronic inflammatory diseases involves a long-term use of anti-inflammatory drugs such as …

Because of the short half-life, either systemic or local administration of bFGF shows
significant drawbacks to spinal injury. In this study, an acellular spinal cord scaffold (ASC) …

Purpose: This study aimed to develop a clinically feasible and practical therapy for multi-
ocular protection following ocular injury by using a thermosensitive drug delivery system …

Purpose: Tumor necrosis factor (TNF)-α is upregulated in eyes following corneal alkali injury
and contributes to corneal and also retinal damage. Prompt TNF-α inhibition by systemic …

Purpose: To review clinical aspects and cellular and molecular steps in the development of
long-term glaucoma after corneal surgery or acute trauma—especially the pivotal role of …

Uveitis refers to a broad group of inflammatory disorders of the eye that often require
medical and surgical management to improve or stabilize vision and prevent vision …

Introduction The short lifetime of protein-based therapies has largely limited their therapeutic
efficacy in injured nervous post-spinal cord injury (post-SCI). Methods In this study, an …