Organoids and organs-on-chips are two rapidly emerging 3D cell culture techniques that
aim to bridge the gap between in vitro 2D cultures and animal models to enable clinically …

Organoids show great potential in clinical translational research owing to their intriguing
properties to represent a near physiological model for native tissues. However, the …

Microplastic particles (MP) are prevalent in both industrial production and the natural
environment, posing a significant concern for human health. Daily diet, air inhalation, and …

Stem cell‐derived kidney organoids contain nephron segments that recapitulate
morphological and functional aspects of the human kidney. However, directed differentiation …

Tremendous progress has been made in the field of toxicology leading to the advance of
developmental toxicity assessment. Conventional animal models and in vitro two …

Time-lapse mechanical properties of stem cell derived cardiac organoids are important
biological cues for understanding contraction dynamics of human heart tissues …

Medicine today faces the combined challenge of an increasing number of untreatable
diseases and fewer drugs reaching the clinic. While pharmaceutical companies have …

Cardiovascular diseases remain the leading cause of death worldwide; hence there is an
increasing focus on developing physiologically relevant in vitro cardiovascular tissue …

Polybrominated diphenyl ethers (PBDEs) serve as brominated flame retardants which
continue to receive considerable attention because of their persistence, bioaccumulation …

Organoids are tiny, self-organized, three-dimensional tissue cultures that are derived from
the differentiation of stem cells. The growing interest in the use of organoids arises from their …