Diabetic retinopathy (DR) causes significant visual loss on a global scale. Treatments for the
vision-threatening complications of diabetic macular edema (DME) and proliferative diabetic …

Retinopathy of prematurity (ROP) is a retinal vasoproliferative disease that affects premature
infants. Despite improvements in neonatal care and management guidelines, ROP remains …

Diabetic retinopathy (DR) is the most common microangiopathic complication of diabetes
mellitus, representing a major cause of visual impairment in developed countries …

Diabetic retinopathy (DR) is the leading cause of visual impairment in the working‐age
population of the Western world. The pathogenesis of DR is complex and several vascular …

Human erythropoietin (EPO) is an N-linked glycoprotein consisting of 166 aa that is
produced in the kidney during the adult life and acts both as a peptide hormone and …

The immature retinas of preterm neonates are susceptible to insults that disrupt
neurovascular growth, leading to retinopathy of prematurity. Suppression of growth factors …

The mouse retina has been used extensively over the past decades to study both
physiologic and pathologic angiogenesis. Over time, various mouse retina models have …

Collectively, angiogenic ocular conditions represent the leading cause of irreversible vision
loss in developed countries. In the US, for example, retinopathy of prematurity, diabetic …

The retinal pigment epithelium (RPE) is an specialized epithelium lying in the interface
between the neural retina and the choriocapillaris where it forms the outer blood‐retinal …

The Wnt signaling pathway plays a pivotal role in vascular morphogenesis in various organs
including the eye. Wnt ligands and receptors are key regulators of ocular angiogenesis both …