Obstructive sleep apnea: current perspectives
AM Osman, SG Carter, JC Carberry… - Nature and science of …, 2018 - Taylor & Francis
The prevalence of obstructive sleep apnea (OSA) continues to rise. So too do the health,
safety, and economic consequences. On an individual level, the causes and consequences …
safety, and economic consequences. On an individual level, the causes and consequences …
Phenotypic approaches to obstructive sleep apnoea–new pathways for targeted therapy
DJ Eckert - Sleep medicine reviews, 2018 - Elsevier
People develop obstructive sleep apnoea (OSA) for different reasons. The ability to
understand these reasons, easily identify them in individual patients, and develop therapies …
understand these reasons, easily identify them in individual patients, and develop therapies …
Evaluation and management of adults with obstructive sleep apnea syndrome
JJ Lee, KM Sundar - Lung, 2021 - Springer
Obstructive sleep apnea syndrome (OSAS) is a common and underdiagnosed medical
condition characterized by recurrent sleep-dependent pauses and reductions in airflow …
condition characterized by recurrent sleep-dependent pauses and reductions in airflow …
International consensus statement on obstructive sleep apnea
JL Chang, AN Goldberg, JA Alt… - International forum of …, 2023 - Wiley Online Library
Background Evaluation and interpretation of the literature on obstructive sleep apnea (OSA)
allows for consolidation and determination of the key factors important for clinical …
allows for consolidation and determination of the key factors important for clinical …
Personalized management approach for OSA
JC Carberry, J Amatoury, DJ Eckert - Chest, 2018 - Elsevier
OSA is a heterogeneous disorder. If left untreated, it has major health, safety, and economic
consequences. In addition to varying levels of impairment in pharyngeal anatomy …
consequences. In addition to varying levels of impairment in pharyngeal anatomy …
Phenotyping pharyngeal pathophysiology using polysomnography in patients with obstructive sleep apnea
Rationale: Therapies for obstructive sleep apnea (OSA) could be administered on the basis
of a patient's own phenotypic causes (“traits”) if a clinically applicable approach were …
of a patient's own phenotypic causes (“traits”) if a clinically applicable approach were …
Endotypes and phenotypes in obstructive sleep apnea
A Malhotra, O Mesarwi, JL Pepin… - Current opinion in …, 2020 - journals.lww.com
OSA is a heterogeneous disease with highly varying underlying mechanisms. OSA has
variable clinical manifestations with definable subsets having risk of particular …
variable clinical manifestations with definable subsets having risk of particular …
More than the sum of the respiratory events: personalized medicine approaches for obstructive sleep apnea
Traditionally, the presence and severity of obstructive sleep apnea (OSA) have been defined
by the apnea–hypopnea index (AHI). Continuous positive airway pressure is generally first …
by the apnea–hypopnea index (AHI). Continuous positive airway pressure is generally first …
Quantifying the arousal threshold using polysomnography in obstructive sleep apnea
Abstract Study Objectives Precision medicine for obstructive sleep apnea (OSA) requires
noninvasive estimates of each patient's pathophysiological “traits.” Here, we provide the first …
noninvasive estimates of each patient's pathophysiological “traits.” Here, we provide the first …
Anatomical determinants of upper airway collapsibility in obstructive sleep apnea: a systematic review and meta-analysis
PJ Hartfield, J Janczy, A Sharma, HA Newsome… - Sleep Medicine …, 2023 - Elsevier
Upper airway (UA) collapsibility is one of the key factors that determine the severity of
obstructive sleep apnea (OSA). Interventions for OSA are aimed at reducing UA …
obstructive sleep apnea (OSA). Interventions for OSA are aimed at reducing UA …