Incidence of malignancy in adult patients with rheumatoid arthritis: a meta-analysis

TA Simon, A Thompson, KK Gandhi… - Arthritis research & …, 2015 - Springer
Introduction Patients with rheumatoid arthritis (RA) are at an increased risk of malignancies
compared with the general population. This has raised concerns regarding these patients …

The safety and side effects of monoclonal antibodies

TT Hansel, H Kropshofer, T Singer, JA Mitchell… - Nature reviews Drug …, 2010 - nature.com
Monoclonal antibodies (mAbs) are now established as targeted therapies for malignancies,
transplant rejection, autoimmune and infectious diseases, as well as a range of new …

Active-comparator design and new-user design in observational studies

K Yoshida, DH Solomon, SC Kim - Nature Reviews Rheumatology, 2015 - nature.com
Over the past decade, an increasing number of observational studies have examined the
effectiveness or safety of treatments for rheumatoid arthritis. Unlike randomized controlled …

Risk of melanoma and nonmelanoma skin cancer among patients with inflammatory bowel disease

MD Long, CF Martin, CA Pipkin, HH Herfarth… - Gastroenterology, 2012 - Elsevier
BACKGROUND & AIMS: Patients with inflammatory bowel disease (IBD) are at risk for
certain malignancies. We aimed to determine the risk of melanoma and nonmelanoma skin …

Malignancies associated with tumour necrosis factor inhibitors in registries and prospective observational studies: a systematic review and meta-analysis

X Mariette, M Matucci-Cerinic, K Pavelka… - Annals of the …, 2011 - ard.bmj.com
Objectives This project was undertaken to assess the risk of malignancy in patients with
rheumatoid arthritis treated with tumour necrosis factor inhibitors (TNFi) in clinical practice …

Use of biologics in rheumatoid arthritis: current and emerging paradigms of care

JR Curtis, JA Singh - Clinical therapeutics, 2011 - Elsevier
Background Improved understanding of rheumatoid arthritis (RA) pathogenesis has led to
the development of new biologic treatments that target specific elements of RA inflammatory …

Comorbidities in rheumatoid arthritis

K Michaud, F Wolfe - Best practice & research Clinical rheumatology, 2007 - Elsevier
Rheumatoid arthritis (RA) is often characterized by the burden of swollen joints, pain, and
decreased physical function, but less understood are the many manifestations of additional …

Risk of malignancies in patients with rheumatoid arthritis treated with biologic therapy: a meta-analysis

MA Lopez-Olivo, JH Tayar, JA Martinez-Lopez… - Jama, 2012 - jamanetwork.com
Context Concerns exist regarding the potential development of malignancies in patients with
rheumatoid arthritis (RA) who are receiving biologic response modifiers (BRMs). Objective …

A meta-analysis of the incidence of malignancy in adult patients with rheumatoid arthritis

AL Smitten, TA Simon, MC Hochberg… - Arthritis research & …, 2008 - Springer
Introduction The risk of malignancies in patients with rheumatoid arthritis (RA) has raised
some concern, particularly with immunosuppressive approaches to disease management …

Current evidence for the management of rheumatoid arthritis with biological disease-modifying antirheumatic drugs: a systematic literature review informing the …

JL Nam, KL Winthrop, RF van Vollenhoven… - Annals of the …, 2010 - ard.bmj.com
Objectives To review the evidence for the efficacy and safety of biological agents in patients
with rheumatoid arthritis (RA) to provide data to develop treatment recommendations by the …