Tranexamic acid, a synthetic derivative of the amino acid lysine, is an antifibrinolytic agent
that acts by binding to plasminogen and blocking the interaction of plasmin (ogen) with …

BACKGROUND: A minority of patients having cardiac procedures (15% to 20%) consume
more than 80% of the blood products transfused at operation. Blood must be viewed as a …

Whenever possible, the recommendations listed in this document are evidence based.
Articles reviewed in this guideline revision covered evidence from the past 10 years through …

Background The relative benefits and risks of performing coronary-artery bypass grafting
(CABG) with a beating-heart technique (off-pump CABG), as compared with …

Background Coronary-artery bypass grafting (CABG) has traditionally been performed with
the use of cardiopulmonary bypass (on-pump CABG). CABG without cardiopulmonary …

Background High-flow nasal cannulae (HFNCs) create positive oropharyngeal airway
pressure, but it is unclear how their use affects lung volume. Electrical impedance …

2011 ACCF/AHA Guideline for Coronary Artery Bypass Graft Surgery: Executive Summary |
Circulation Science Volunteer Warning signs SearchSearch Advanced Search Donate …

The most common medical cause of major blood loss is surgery, particularly cardiovascular
procedures, liver transplantation and hepatic resection, and major orthopedic procedures …

A Report of the American College of Cardiology Foundation/American Heart Association
Task Force on Practice Guidelines

Background Coronary artery bypass grafting (CABG) is performed both without and with
cardiopulmonary bypass, referred to as off‐pump and on‐pump CABG respectively …