Background The projected rise in the incidence of type 2 diabetes mellitus (T2DM) could
develop into a substantial health problem worldwide. Whether diet, physical activity or both …

Primary aging is the progressive and inevitable process of bodily deterioration during
adulthood. In skeletal muscle, primary aging causes defective mitochondrial energetics and …

Objective Development of these guidelines is mandated by the American Association of
Clinical Endocrinologists (AACE) Board of Directors and the American College of …

Objective To measure long‐term changes in resting metabolic rate (RMR) and body
composition in participants of “The Biggest Loser” competition. Methods Body composition …

Objectives The National Institutes of Health, led by the National Heart, Lung, and Blood
Institute, organized a working group of experts to discuss the problem of weight regain after …

OBJECTIVE To assess participant-level results from the first 4 years of implementation of the
National Diabetes Prevention Program (National DPP), a national effort to prevent type 2 …

Objective To evaluate 8‐year weight losses achieved with intensive lifestyle intervention (ILI)
in the Look AHEAD (Action for Health in Diabetes) study. Design and Methods Look AHEAD …

Background: Trials have shown efficacy of rigorous diet and physical activity promotion
programs to reduce diabetes incidence and improve glycemic measures in adults at …

Abstract The American Cancer Society (ACS) publishes Nutrition and Physical Activity
Guidelines to serve as a foundation for its communication, policy, and community strategies …

To achieve good metabolic control in diabetes and keep long term, a combination of
changes in lifestyle and pharmacological treatment is necessary. Achieving near-normal …