[HTML][HTML] MUC1 and MUC16: critical for immune modulation in cancer therapeutics
X Chen, IK Sandrine, M Yang, J Tu, X Yuan - Frontiers in immunology, 2024 - frontiersin.org
The Mucin (MUC) family, a range of highly glycosylated macromolecules, is ubiquitously
expressed in mammalian epithelial cells. Such molecules are pivotal in establishing …
expressed in mammalian epithelial cells. Such molecules are pivotal in establishing …
[HTML][HTML] Digital platforms enabling single-molecule analysis for cancer detection
J Li, Z Zhang, M Trau, A Wuethrich - TrAC Trends in Analytical Chemistry, 2023 - Elsevier
The current paradigm of cancer management relies on imaging modalities and tissue biopsy
to characterize the tumor landscape and devise treatment. As a complementary approach to …
to characterize the tumor landscape and devise treatment. As a complementary approach to …
Colorimetric detection of sepsis-derived hyperdegranulation with plasmonic nanosensors
G Santopolo, A Clemente, M Aranda, A Socias… - ACS …, 2021 - ACS Publications
Hyperdegranulation of neutrophilic granulocytes is a common finding in sepsis that directly
contributes to the heightened immune response leading to organ dysfunction. Currently, cell …
contributes to the heightened immune response leading to organ dysfunction. Currently, cell …
Machine learning color feature analysis of a high throughput nanoparticle conjugate sensing assay
D Bennett, X Chen, GJ Walker, S Stelzer-Braid… - Analytical …, 2023 - ACS Publications
Plasmonic nanoparticles are finding applications within the single molecule sensing field in
a “dimer” format, where interaction of the target with hairpin DNA causes a decrease in the …
a “dimer” format, where interaction of the target with hairpin DNA causes a decrease in the …
[HTML][HTML] The three laws of nano-robotics
MJ Sailor - ACS sensors, 2023 - ACS Publications
Last month's ACS Sensors editorial, by Soo-Yeon Cho and Hee-Tae Jung, highlighted some
of the promises and challenges of artificial intelligence software such as ChatGPT. 1 The …
of the promises and challenges of artificial intelligence software such as ChatGPT. 1 The …
Recent progress in plasmonic nanoparticle‐based biomarker detection and cytometry for the study of central nervous system disorders
Neurological disorders affect hundreds of millions of people around the world, are often life‐
threatening, untreatable, and can result in debilitating symptoms. The high prevalence of …
threatening, untreatable, and can result in debilitating symptoms. The high prevalence of …
[HTML][HTML] Characterization of cell-bound CA125 on immune cell subtypes of ovarian cancer patients using a novel imaging platform
G González, K Lakatos, J Hoballah, R Fritz-Klaus… - Cancers, 2021 - mdpi.com
Simple Summary High-grade serous ovarian cancer is a fatal disease typically detected at
an advanced stage when options for effective treatment are significantly limited. The lack of …
an advanced stage when options for effective treatment are significantly limited. The lack of …
[HTML][HTML] Application of a novel microscopic technique for quantifying CA125 binding to circulating mononuclear cells in longitudinal specimens during treatment for …
K Lakatos, G González, J Hoballah, J Brooker… - Journal of Ovarian …, 2022 - Springer
Background Measurement of serum CA125, an antigenic fragment of human mucin 16
(MUC16), is used to monitor the clinical progression of epithelial ovarian cancer (EOC) …
(MUC16), is used to monitor the clinical progression of epithelial ovarian cancer (EOC) …
Identifying novel ovarian tumor biomarkers through mining of the transcriptome of circulating immune cells: A proof‐of‐concept study
S Uppal, E Medlin, M Felder, A Kapur… - American Journal of …, 2021 - Wiley Online Library
Objective Treatment of high‐grade serous ovarian cancer (HGSOC) will benefit from early
detection of cancer. Here, we provide proof‐of‐concept data supporting the hypothesis that …
detection of cancer. Here, we provide proof‐of‐concept data supporting the hypothesis that …
子宫内膜异位症相关性卵巢癌发病风险模型构建及验证
言娜, 邹丽莎, 汤洁, 张伶俐 - 循证医学, 2022 - jebm.cn
目的探讨基于列线图模型预测子宫内膜异位症(endometriosis, EMT) 恶变的价值.
方法回顾性选取2015 年1 月至2020 年6 月在湖南中医药高等专科学校附属第一医院就诊并 …
方法回顾性选取2015 年1 月至2020 年6 月在湖南中医药高等专科学校附属第一医院就诊并 …