[HTML][HTML] MUC1 and MUC16: critical for immune modulation in cancer therapeutics

X Chen, IK Sandrine, M Yang, J Tu, X Yuan - Frontiers in immunology, 2024 - frontiersin.org
The Mucin (MUC) family, a range of highly glycosylated macromolecules, is ubiquitously
expressed in mammalian epithelial cells. Such molecules are pivotal in establishing …

[HTML][HTML] Digital platforms enabling single-molecule analysis for cancer detection

J Li, Z Zhang, M Trau, A Wuethrich - TrAC Trends in Analytical Chemistry, 2023 - Elsevier
The current paradigm of cancer management relies on imaging modalities and tissue biopsy
to characterize the tumor landscape and devise treatment. As a complementary approach to …

Colorimetric detection of sepsis-derived hyperdegranulation with plasmonic nanosensors

G Santopolo, A Clemente, M Aranda, A Socias… - ACS …, 2021 - ACS Publications
Hyperdegranulation of neutrophilic granulocytes is a common finding in sepsis that directly
contributes to the heightened immune response leading to organ dysfunction. Currently, cell …

Machine learning color feature analysis of a high throughput nanoparticle conjugate sensing assay

D Bennett, X Chen, GJ Walker, S Stelzer-Braid… - Analytical …, 2023 - ACS Publications
Plasmonic nanoparticles are finding applications within the single molecule sensing field in
a “dimer” format, where interaction of the target with hairpin DNA causes a decrease in the …

[HTML][HTML] The three laws of nano-robotics

MJ Sailor - ACS sensors, 2023 - ACS Publications
Last month's ACS Sensors editorial, by Soo-Yeon Cho and Hee-Tae Jung, highlighted some
of the promises and challenges of artificial intelligence software such as ChatGPT. 1 The …

Recent progress in plasmonic nanoparticle‐based biomarker detection and cytometry for the study of central nervous system disorders

F Peng, S Jeong, A Ho, CL Evans - Cytometry Part A, 2021 - Wiley Online Library
Neurological disorders affect hundreds of millions of people around the world, are often life‐
threatening, untreatable, and can result in debilitating symptoms. The high prevalence of …

[HTML][HTML] Characterization of cell-bound CA125 on immune cell subtypes of ovarian cancer patients using a novel imaging platform

G González, K Lakatos, J Hoballah, R Fritz-Klaus… - Cancers, 2021 - mdpi.com
Simple Summary High-grade serous ovarian cancer is a fatal disease typically detected at
an advanced stage when options for effective treatment are significantly limited. The lack of …

[HTML][HTML] Application of a novel microscopic technique for quantifying CA125 binding to circulating mononuclear cells in longitudinal specimens during treatment for …

K Lakatos, G González, J Hoballah, J Brooker… - Journal of Ovarian …, 2022 - Springer
Background Measurement of serum CA125, an antigenic fragment of human mucin 16
(MUC16), is used to monitor the clinical progression of epithelial ovarian cancer (EOC) …

Identifying novel ovarian tumor biomarkers through mining of the transcriptome of circulating immune cells: A proof‐of‐concept study

S Uppal, E Medlin, M Felder, A Kapur… - American Journal of …, 2021 - Wiley Online Library
Objective Treatment of high‐grade serous ovarian cancer (HGSOC) will benefit from early
detection of cancer. Here, we provide proof‐of‐concept data supporting the hypothesis that …

子宫内膜异位症相关性卵巢癌发病风险模型构建及验证

言娜, 邹丽莎, 汤洁, 张伶俐 - 循证医学, 2022 - jebm.cn
目的探讨基于列线图模型预测子宫内膜异位症(endometriosis, EMT) 恶变的价值.
方法回顾性选取2015 年1 月至2020 年6 月在湖南中医药高等专科学校附属第一医院就诊并 …