Antiseizure medications for adults with epilepsy: a review

AM Kanner, MM Bicchi - Jama, 2022 - jamanetwork.com
Importance Epilepsy affects approximately 65 million people worldwide. Persistent seizures
are associated with a 20% to 40% risk of bodily injuries (eg, fractures, burns, concussions) …

Epilepsy in China: major progress in the past two decades

D Ding, D Zhou, JW Sander, W Wang, S Li… - The Lancet …, 2021 - thelancet.com
China has approximately 10 million people with epilepsy. There is a vast epilepsy treatment
gap in China, mainly driven by deficiencies in health-care delivery and social discrimination …

EASL clinical practice guidelines: drug-induced liver injury

RJ Andrade, GP Aithal, ES Björnsson, N Kaplowitz… - Journal of …, 2019 - Elsevier
Idiosyncratic (unpredictable) drug-induced liver injury is one of the most challenging liver
disorders faced by hepatologists, because of the myriad of drugs used in clinical practice …

Clinical Pharmacogenetics Implementation Consortium Guideline for HLA Genotype and Use of Carbamazepine and Oxcarbazepine: 2017 Update

EJ Phillips, C Sukasem, M Whirl‐Carrillo… - Clinical …, 2018 - Wiley Online Library
The variant allele HLA‐B* 15: 02 is strongly associated with greater risk of Stevens–Johnson
syndrome (SJS) and toxic epidermal necrolysis (TEN) in patients treated with …

Adverse effects of antiepileptic drugs

P Perucca, FG Gilliam - The lancet neurology, 2012 - thelancet.com
More than 150 years after bromide was introduced as the first antiepileptic drug, adverse
effects remain a leading cause of treatment failure and a major determinant of impaired …

Toxic epidermal necrolysis and Stevens-Johnson syndrome

T Harr, LE French - Orphanet journal of rare diseases, 2010 - Springer
Toxic epidermal necrolysis (TEN) and Stevens Johnson Syndrome (SJS) are severe
adverse cutaneous drug reactions that predominantly involve the skin and mucous …

[HTML][HTML] Carbamazepine-induced toxic effects and HLA-B* 1502 screening in Taiwan

P Chen, JJ Lin, CS Lu, CT Ong, PF Hsieh… - … England Journal of …, 2011 - Mass Medical Soc
Background Carbamazepine, an anticonvulsant and a mood-stabilizing drug, is the main
cause of the Stevens–Johnson syndrome (SJS) and its related disease, toxic epidermal …

Impact of predictive, preventive and precision medicine strategies in epilepsy

R Nabbout, M Kuchenbuch - Nature Reviews Neurology, 2020 - nature.com
Over the last decade, advances in genetics, neuroimaging and EEG have enabled the
aetiology of epilepsy to be identified earlier in the disease course than ever before. At the …

Toxic epidermal necrolysis: Part I. Introduction, history, classification, clinical features, systemic manifestations, etiology, and immunopathogenesis

RA Schwartz, PH McDonough, BW Lee - Journal of the American Academy …, 2013 - Elsevier
Toxic epidermal necrolysis is a life-threatening, typically drug-induced mucocutaneous
disease. It is clinically characterized as a widespread sloughing of the skin and mucosa …

Stevens–Johnson syndrome and toxic epidermal necrolysis: an update

RP Dodiuk-Gad, WH Chung… - American journal of …, 2015 - Springer
Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are life-threatening
mucocutaneous reactions, predominantly drug induced. The mortality rates for SJS and TEN …