Research progress on the mechanism of sepsis induced myocardial injury

CF Bi, J Liu, LS Yang, JF Zhang - Journal of inflammation research, 2022 - Taylor & Francis
Sepsis is an abnormal condition with multiple organ dysfunctions caused by the
uncontrolled infection response and one of the major diseases that seriously hang over …

Marine based natural products: Exploring the recent developments in the identification of antimicrobial agents

A Krishna MS, S Mohan, KT Ashitha… - Chemistry & …, 2022 - Wiley Online Library
The marine ecosystem is the less explored, biologically diverse, and vastest resource to
discover novel antimicrobial agents. In recent decades' antimicrobial drugs are losing their …

Antibacterial natural products from microbial and fungal sources: A decade of advances

S Mohan, MS Ajay Krishna, M Chandramouli, RS Keri… - Molecular Diversity, 2023 - Springer
Throughout the ages the world has witnessed the outbreak of many infectious diseases.
Emerging microbial diseases pose a serious threat to public health. Increasing resistance of …

Mitochondria-endoplasmic reticulum contacts in sepsis-induced myocardial dysfunction

T Jiang, Q Wang, J Lv, L Lin - Frontiers in Cell and Developmental …, 2022 - frontiersin.org
Mitochondrial and endoplasmic reticulum (ER) are important intracellular organelles. The
sites that mitochondrial and ER are closely related in structure and function are called …

Quercetin alleviates LPS-stimulated myocardial injury through regulating ALOX5/PI3K/AKT pathway in sepsis

F Guan, H Du, J Li, H Ren, A Dong - Cardiovascular Toxicology, 2024 - Springer
Quercetin (QUE) has been found to inhibit the progression of sepsis-related diseases,
including sepsis-induced cardiomyopathy (SIC). More information about the role and …

LncRNA MALAT1 regulates USP22 expression through EZH2-mediated H3K27me3 modification to accentuate sepsis-induced myocardial dysfunction

H Xu, W Ye, B Shi - Cardiovascular Toxicology, 2022 - Springer
Metastasis-associated lung adenocarcinoma transcript 1 (MALAT1), a long non-coding RNA
(lncRNA), has been confirmed to recruit enhancer of zeste 2 polycomb repressive complex 2 …

脓毒症心肌损伤发病机制及治疗研究进展.

黄颖, 唐立丽, 关于琳, 张杰… - Journal of Practical …, 2023 - search.ebscohost.com
脓毒症是宿主对感染反应失控而导致的器官功能障碍, 是急危重症患者常见的死亡原因.
脓毒症心肌损伤(sepsis⁃ induced myocardial injury, SIMI) 与脓毒症不良预后直接相关 …

Carvacrol alleviates LPS-induced myocardial dysfunction by inhibiting the TLR4/MyD88/NF-κB and NLRP3 inflammasome in cardiomyocytes

L Xu, X Yang, XT Liu, XY Li, HZ Zhu, YH Xie… - Journal of …, 2024 - Springer
Background Sepsis-induced myocardial dysfunction (SIMD) may contribute to the poor
prognosis of septic patients. Carvacrol (2-methyl-5-isopropyl phenol), a phenolic …

Oxymatrine antagonises oxidative stress and apoptosis in Nemopilema nomurai toxin-induced cardiotoxicity by inhibiting mitogen-activated protein kinase

X Wang, Y Wang, X Geng, Z Wang, J Zhang, T Liu… - Toxicology Letters, 2024 - Elsevier
Jellyfish stings can trigger abrupt heart failure via toxins, leading acute mortality rise.
Proposed mechanisms involve oxidative stress and apoptosis, but evidence for effective …

Pharmaceutical Potential of Remedial Plants and Helminths for Treating Inflammatory Bowel Disease

T Jamtsho, A Loukas, P Wangchuk - Pharmaceuticals, 2024 - mdpi.com
Research is increasingly revealing that inflammation significantly contributes to various
diseases, particularly inflammatory bowel disease (IBD). IBD is a major medical challenge …