[HTML][HTML] The molecular mechanisms of cuproptosis and its relevance to cardiovascular disease
D Wang, Z Tian, P Zhang, L Zhen, Q Meng… - Biomedicine & …, 2023 - Elsevier
Recently, cuproptosis has been demonstrated to be a new non-apototic cell death mode that
is characterized by copper dependence and the regulation of mitochondrial respiration …
is characterized by copper dependence and the regulation of mitochondrial respiration …
The molecular mechanisms of defective copper metabolism in diabetic cardiomyopathy
X Cui, Y Wang, H Liu, M Shi, J Wang… - Oxidative Medicine and …, 2022 - Wiley Online Library
Copper is an essential trace metal element that significantly affects human physiology and
pathology by regulating various important biological processes, including mitochondrial …
pathology by regulating various important biological processes, including mitochondrial …
[HTML][HTML] ATF3/SPI1/SLC31A1 signaling promotes cuproptosis induced by advanced glycosylation end products in diabetic myocardial injury
S Huo, Q Wang, W Shi, L Peng, Y Jiang, M Zhu… - International Journal of …, 2023 - mdpi.com
Cuproptosis resulting from copper (Cu) overload has not yet been investigated in diabetic
cardiomyopathy (DCM). Advanced glycosylation end products (AGEs) induced by persistent …
cardiomyopathy (DCM). Advanced glycosylation end products (AGEs) induced by persistent …
[HTML][HTML] An emerging role of defective copper metabolism in heart disease
Y Liu, J Miao - Nutrients, 2022 - mdpi.com
Copper is an essential trace metal element that significantly affects human physiology and
pathology by regulating various important biological processes, including mitochondrial …
pathology by regulating various important biological processes, including mitochondrial …
Molecular strategies to prevent, inhibit, and degrade advanced glycoxidation and advanced lipoxidation end products
The advanced glycoxidation end products (AGEs) and lipoxidation end products (ALEs)
contribute to the development of diabetic complications and of other pathologies. The review …
contribute to the development of diabetic complications and of other pathologies. The review …
The role of zinc, copper and iron in the pathogenesis of diabetes and diabetic complications: therapeutic effects by chelators
Y Zheng, XK Li, Y Wang, L Cai - Hemoglobin, 2008 - Taylor & Francis
Zinc (Zn), copper (Cu) and iron (Fe) are essential minerals that are required for a variety of
biomolecules to maintain the normal structure, function, and proliferation of cells. These …
biomolecules to maintain the normal structure, function, and proliferation of cells. These …
A newly identified polysaccharide from Ganoderma atrum attenuates hyperglycemia and hyperlipidemia
K Zhu, S Nie, C Li, S Lin, M Xing, W Li, D Gong… - International journal of …, 2013 - Elsevier
A polysaccharide from Ganoderma atrum (PSG-1) was purified and characterized, and its
hypoglycemic and hypolipidemic effects were investigated in high fat diet-and streptozotocin …
hypoglycemic and hypolipidemic effects were investigated in high fat diet-and streptozotocin …
Dissecting copper homeostasis in diabetes mellitus
J Lowe, R Taveira‐da‐Silva, E Hilário‐Souza - Iubmb Life, 2017 - Wiley Online Library
Diabetes Mellitus (DM) is characterized by elevated blood glucose levels (hyperglycemia). It
can occur due to impaired secretion or action of the hormone insulin, which is produced by …
can occur due to impaired secretion or action of the hormone insulin, which is produced by …
Therapeutic potential of copper chelation with triethylenetetramine in managing diabetes mellitus and Alzheimer's disease
GJS Cooper - Drugs, 2011 - Springer
This article reviews recent evidence, much of which has been generated by my group's
research programme, which has identified for the first time a previously unknown copper …
research programme, which has identified for the first time a previously unknown copper …
[HTML][HTML] Role of trientine in hypertrophic cardiomyopathy: A review of mechanistic aspects
Abnormality in myocardial copper homeostasis is believed to contribute to the development
of cardiomyopathy. Trientine, a copper-chelating drug used in the management of patients …
of cardiomyopathy. Trientine, a copper-chelating drug used in the management of patients …