Background: As called for by the Sustainable Development Goals, governments,
development partners and civil society are working on anti-corruption, transparency and …

Background Abstracts of presentations at scientific meetings are usually available only in
conference proceedings. If subsequent full publication of results reported in these abstracts …

Objectives To ascertain compliance rates with the European Commission's requirement that
all trials on the EU Clinical Trials Register (EUCTR) post results to the registry within 12 …

Background Dickersin and Min define publication bias as the failure to publish the results of
a study 'on the basis of the direction or strength of the study findings'. 1 This non-publication …

Background Valid assessment of drug efficacy and safety requires an evidence base free of
reporting bias. Using trial reports in Food and Drug Administration (FDA) drug approval …

Background A meta-analysis as part of a systematic review aims to provide a thorough,
comprehensive and unbiased statistical summary of data from the literature. However …

In the context of avoiding research waste, the conduct of a feasibility study before a clinical
trial should reduce the risk that further resources will be committed to a trial that is likely to …

Strengthening Research through Data Sharing | New England Journal of Medicine Skip to main
content The New England Journal of Medicine homepage Advanced Search SEARCH …

Real-world evidence (RWE) is the clinical evidence about benefits or risks of medical
products derived from analyzing real world data (RWD), which are data collected through …

In a clinical trial, people with the same disease can show different responses after treatment
with the same drug and exactly under the same conditions. Some of them may improve …