Role of thymic stromal lymphopoietin in allergy and beyond
R Ebina-Shibuya, WJ Leonard - Nature Reviews Immunology, 2023 - nature.com
Thymic stromal lymphopoietin (TSLP) is a pleiotropic cytokine that acts on multiple cell
lineages, including dendritic cells, T cells, B cells, neutrophils, mast cells, eosinophils and …
lineages, including dendritic cells, T cells, B cells, neutrophils, mast cells, eosinophils and …
The cytokines of asthma
BN Lambrecht, H Hammad, JV Fahy - Immunity, 2019 - cell.com
Asthma is a chronic inflammatory airway disease associated with type 2 cytokines
interleukin-4 (IL-4), IL-5, and IL-13, which promote airway eosinophilia, mucus …
interleukin-4 (IL-4), IL-5, and IL-13, which promote airway eosinophilia, mucus …
A cellular census of human lungs identifies novel cell states in health and in asthma
Human lungs enable efficient gas exchange and form an interface with the environment,
which depends on mucosal immunity for protection against infectious agents. Tightly …
which depends on mucosal immunity for protection against infectious agents. Tightly …
The atopic march: critical evidence and clinical relevance
DA Hill, JM Spergel - Annals of Allergy, Asthma & Immunology, 2018 - Elsevier
The atopic march refers to the natural history of allergic diseases as they develop during
infancy and childhood. Introduced by the American allergists AF Coca and RA Cooke in …
infancy and childhood. Introduced by the American allergists AF Coca and RA Cooke in …
Effects of an anti-TSLP antibody on allergen-induced asthmatic responses
GM Gauvreau, PM O'Byrne, LP Boulet… - … England Journal of …, 2014 - Mass Medical Soc
Background Thymic stromal lymphopoietin (TSLP) is an epithelial-cell–derived cytokine that
may be important in initiating allergic inflammation. AMG 157 is a human anti-TSLP …
may be important in initiating allergic inflammation. AMG 157 is a human anti-TSLP …
Thymic stromal lymphopoietin isoforms, inflammatory disorders, and cancer
G Varricchi, A Pecoraro, G Marone… - Frontiers in …, 2018 - frontiersin.org
Thymic stromal lymphopoietin (TSLP) is a pleiotropic cytokine originally isolated from a
murine thymic stromal cell line. TSLP exerts its biological effects by binding to a high-affinity …
murine thymic stromal cell line. TSLP exerts its biological effects by binding to a high-affinity …
The atopic march: current insights into skin barrier dysfunction and epithelial cell‐derived cytokines
H Han, F Roan, SF Ziegler - Immunological reviews, 2017 - Wiley Online Library
Atopic dermatitis often precedes the development of other atopic diseases. The atopic march
describes this temporal relationship in the natural history of atopic diseases. Although the …
describes this temporal relationship in the natural history of atopic diseases. Although the …
The airway epithelium in asthma
BN Lambrecht, H Hammad - Nature medicine, 2012 - nature.com
Asthma is a T lymphocyte–controlled disease of the airway wall caused by inflammation,
overproduction of mucus and airway wall remodeling leading to bronchial hyperreactivity …
overproduction of mucus and airway wall remodeling leading to bronchial hyperreactivity …
The genetics of asthma and allergic disease: a 21st century perspective
Asthma and allergy are common conditions with complex etiologies involving both genetic
and environmental contributions. Recent genome‐wide association studies (GWAS) and …
and environmental contributions. Recent genome‐wide association studies (GWAS) and …
Asthma phenotypes and IgE responses
A Froidure, J Mouthuy, SR Durham… - European …, 2016 - Eur Respiratory Soc
The discovery of IgE represented a major breakthrough in allergy and asthma research,
whereas the clinical interest given to IgE in asthma has been blurred until the arrival of anti …
whereas the clinical interest given to IgE in asthma has been blurred until the arrival of anti …