Over the past decades in modern medicine, there has been a shift from statistical
significance to clinical relevance when it comes to interpreting results from clinical trials. A …

Scientists are increasingly crossing the boundaries of the professional system by involving
the general public (the crowd) directly in their research. However, this crowd involvement …

Persons with heart failure (HF) often suffer from poor symptom control, decreased quality of
life, and poor communication with their health care providers. These needs are particularly …

Community engagement is considered essential to effectively translate research into
practice and is increasingly recognized as a key to successful clinical trial recruitment …

The global pharmaceutical industry portfolio is skewed towards cancer and rare diseases
due to more predictable development pathways and financial incentives. In contrast, drug …

Background: There is an increasing expectation for research to involve patient stakeholders.
Yet little guidance exists regarding patient-engaged research in evidence synthesis …

Objective The value of patient involvement to the design, conduct, and outcomes of
healthcare research is increasingly being recognized. Patient involvement also provides …

The role of percutaneous coronary interventions in addition to medical therapy for patients
with stable coronary artery disease continues to be debated in routine clinical practice …

Florence Nightingale, nurse and public health practitioner, was a forerunner in outcome
assessment (Appleby J, Devlin N. Measuring success in the NHS. In: Using patient …

Background The updated international draft guidelines, the “General Considerations for
Clinical Studies, ICH E8 (R1)”, state that patient engagement ensures that all perspectives …