The heterogeneity of traumatic brain injury (TBI) is considered one of the most significant
barriers to finding effective therapeutic interventions. In October, 2007, the National Institute …

Object. Increasing age is associated with poorer outcome in patients with closed traumatic
brain injury (TBI). It is uncertain whether critical age thresholds exist, however, and the …

Abstract Introduction Pressure-reactivity index (PRx) is a useful tool in brain monitoring of
trauma patients, but the question remains about its critical values. Using our TBI database …

✓ This study describes the relationship between raised intracranial pressure (ICP),
hypotension, and outcome from severe head injury. The study is based on information …

Delirium, stupor and coma are common clinical states that confront clinicians in almost every
medical specialty. With appropriate diagnosis and treatment, coma can often be treated …

Traumatic brain injury (TBI) is a heterogeneous condition that encompasses a broad
spectrum of disorders. Outcome can be highly variable, particularly in more severely injured …

We studied the prognostic value of a wide range of conventional and novel prognostic
factors on admission after traumatic brain injury (TBI) using both univariate and multivariable …

✓ In this prospective multicenter study, the authors have examined data derived from the
initial computerized tomography (CT) scans of 753 patients with severe head injury. When …

Background This paper introduces the 7/5/2011al Pupil index (NPi), a sensitive measure of
pupil reactivity and an early indicator of increasing intracranial pressure (ICP). This may …

Background Subjective scoring of pupil reactivity is a fundamental element of the
neurological examination for which the pupillometer provides an objective measure …