Strategies for the chemical and biological functionalization of scaffolds for cardiac tissue engineering: a review

M Tallawi, E Rosellini, N Barbani… - Journal of the …, 2015 - royalsocietypublishing.org
The development of biomaterials for cardiac tissue engineering (CTE) is challenging,
primarily owing to the requirement of achieving a surface with favourable characteristics that …

Injectable hydrogels for cardiac tissue engineering

B Peña, M Laughter, S Jett, TJ Rowland… - Macromolecular …, 2018 - Wiley Online Library
In light of the limited efficacy of current treatments for cardiac regeneration, tissue
engineering approaches have been explored for their potential to provide mechanical …

Gold nanorod-incorporated gelatin-based conductive hydrogels for engineering cardiac tissue constructs

A Navaei, H Saini, W Christenson, RT Sullivan, R Ros… - Acta biomaterialia, 2016 - Elsevier
The development of advanced biomaterials is a crucial step to enhance the efficacy of tissue
engineering strategies for treatment of myocardial infarction. Specific characteristics of …

Cardiac tissue engineering: state of the art

MN Hirt, A Hansen, T Eschenhagen - Circulation research, 2014 - Am Heart Assoc
The engineering of 3-dimensional (3D) heart muscles has undergone exciting progress for
the past decade. Profound advances in human stem cell biology and technology, tissue …

Organ engineering based on decellularized matrix scaffolds

JJ Song, HC Ott - Trends in molecular medicine, 2011 - cell.com
End-organ failure is one of the major healthcare challenges in the Western world. Yet, donor
organ shortage and the need for immunosuppression limit the impact of transplantation. The …

[HTML][HTML] Control of crosslinking for tailoring collagen-based scaffolds stability and mechanics

N Davidenko, CF Schuster, DV Bax, N Raynal… - Acta biomaterialia, 2015 - Elsevier
We provide evidence to show that the standard reactant concentrations used in tissue
engineering to cross-link collagen-based scaffolds are up to 100 times higher than required …

A microfabricated platform to measure and manipulate the mechanics of engineered cardiac microtissues

T Boudou, WR Legant, A Mu, MA Borochin… - … Engineering Part A, 2012 - liebertpub.com
Engineered myocardial tissues can be used to elucidate fundamental features of myocardial
biology, develop organotypic in vitro model systems, and as engineered tissue constructs for …

Engineered heart tissue grafts improve systolic and diastolic function in infarcted rat hearts

WH Zimmermann, I Melnychenko, G Wasmeier… - Nature medicine, 2006 - nature.com
The concept of regenerating diseased myocardium by implantation of tissue-engineered
heart muscle is intriguing, but convincing evidence is lacking that heart tissues can be …

Functional assembly of engineered myocardium by electrical stimulation of cardiac myocytes cultured on scaffolds

M Radisic, H Park, H Shing, T Consi… - Proceedings of the …, 2004 - National Acad Sciences
The major challenge of tissue engineering is directing the cells to establish the physiological
structure and function of the tissue being replaced across different hierarchical scales. To …

Fabrication of functional three-dimensional tissues by stacking cell sheets in vitro

Y Haraguchi, T Shimizu, T Sasagawa, H Sekine… - Nature protocols, 2012 - nature.com
The fabrication of 3D tissues retaining the original functions of tissues/organs in vitro is
crucial for optimal tissue engineering and regenerative medicine. The fabrication of 3D …