Intermediate progenitor cells (IPCs) are a type of neurogenic transient amplifying cells in the
developing cerebral cortex. IPCs divide symmetrically at basal (abventricular) positions in …

The immense range of human behaviours is rooted in the complex neural networks of the
cerebrum. The creation of these networks depends on the precise integration of specific …

Microglia are observed in the early developing forebrain and contribute to the regulation of
neurogenesis through still unravelled mechanisms. In the developing cerebral cortex …

Neurodegeneration is the irremediable pathological event occurring during chronic
inflammatory diseases of the CNS. Here we show that, in experimental autoimmune …

Mouse embryos bearing hypomorphic and conditional null Fgf8 mutations have small and
abnormally patterned telencephalons. We provide evidence that the hypoplasia results from …

Recent epidemiological and immunological studies provide evidence for an association
between Epstein–Barr virus infection and multiple sclerosis, suggesting a role of Epstein …

Endogenous neural stem/precursor cells (NPCs) are considered a functional reservoir for
promoting tissue homeostasis and repair after injury, therefore regenerative strategies that …

Neurogenesis does not stop abruptly at birth, but persists in specific brain regions
throughout life. The neural stem cells (NSCs) located in the largest germinal region of the …

Neurogenesis in the developing neocortex is a strictly regulated process of cell division and
differentiation. Here we report that a gradual retreat of canonical Wnt signaling in the cortex …

The foundation for the anatomical and functional complexity of the vertebrate central
nervous system is laid during embryogenesis. After Spemann's organizer and its derivatives …