An ancient conflict between hosts and pathogens has driven the innate and adaptive arms of
immunity. Knowledge about this interplay can not only help us identify biological …

Virus entry, consisting of attachment to and penetration into the host target cell, is the first
step of the virus life cycle and is a critical 'do or die'event that governs virus emergence in …

Animal cells use a wide variety of mechanisms to slow or prevent replication of viruses.
These mechanisms are usually mediated by antiviral proteins whose expression and …

Interferon-induced transmembrane proteins (IFITMs) inhibit infection of diverse enveloped
viruses, including the influenza A virus (IAV) which is thought to enter from late endosomes …

Interferon-induced transmembrane proteins (IFITMs) are a family of small proteins that
localize in the plasma and endolysosomal membranes. IFITMs not only inhibit viral entry into …

The interferon-induced transmembrane (IFITM) proteins protect cells from diverse virus
infections by inhibiting virus-cell fusion. IFITM proteins also inhibit HIV-1 replication through …

The interferon-inducible transmembrane protein (IFITM) family inhibits a growing number of
pathogenic viruses, among them influenza A virus, dengue virus, hepatitis C virus, and …

Interferon‐inducible transmembrane (IFITM) proteins are a family of small homologous
proteins, localized in the plasma and endolysosomal membranes, which confer cellular …

IFNs are a family of cytokines that are essential for the antiviral response in vertebrates. Not
surprisingly, viruses have adapted to encode virulence factors to cope with the IFN …

Interferon-induced transmembrane protein 3 (IFITM3) potently inhibits entry of diverse
enveloped viruses by trapping the viral fusion at a hemifusion stage, but the underlying …