Escaping the endosome: assessing cellular trafficking mechanisms of non-viral vehicles
E Xu, WM Saltzman, AS Piotrowski-Daspit - Journal of Controlled Release, 2021 - Elsevier
Non-viral vehicles hold therapeutic promise in advancing the delivery of a variety of cargos
in vitro and in vivo, including small molecule drugs, biologics, and especially nucleic acids …
in vitro and in vivo, including small molecule drugs, biologics, and especially nucleic acids …
Advances in anti-breast cancer drugs and the application of nano-drug delivery systems in breast cancer therapy
X Fang, J Cao, A Shen - Journal of Drug Delivery Science and Technology, 2020 - Elsevier
Breast cancer is one of the most common malignant tumors among women. Although the
traditional breast cancer therapies are effective, there have numerous shortcomings …
traditional breast cancer therapies are effective, there have numerous shortcomings …
[HTML][HTML] Emerging nanoformulation strategies for phytocompounds and applications from drug delivery to phototherapy to imaging
Over thousands of years, natural bioactive compounds derived from plants (bioactive
phytocompounds, BPCs) have been used worldwide to address human health issues …
phytocompounds, BPCs) have been used worldwide to address human health issues …
Fusion of tumor-derived exosomes with long-circulating and pH-sensitive liposomes loaded with doxorubicin for the treatment of breast cancer
ER Gomes, AT Carvalho, TC Barbosa, LL Ferreira… - AAPS …, 2022 - Springer
Doxorubicin (DOX) is a chemotherapeutic agent that has been used in the treatment of
breast cancer. However, serious toxic effects have limited its use, mainly cardiotoxicity. To …
breast cancer. However, serious toxic effects have limited its use, mainly cardiotoxicity. To …
Nanoliposomes as multidrug carrier of gemcitabine/paclitaxel for the effective treatment of metastatic breast cancer disease: a comparison with Gemzar and Taxol
C Celia, MC Cristiano, F Froiio… - Advanced …, 2021 - Wiley Online Library
Several liposomal drugs have received clinical approval for the treatment of cancer due to
the reduced side effects and/or improved therapeutic efficacy in comparison to their …
the reduced side effects and/or improved therapeutic efficacy in comparison to their …
[HTML][HTML] Preparation, characterization, pharmacokinetics and anticancer effects of PEGylated β-elemene liposomes
B Zhai, Q Wu, W Wang, M Zhang, X Han… - Cancer biology & …, 2020 - ncbi.nlm.nih.gov
Objective: This study aimed to develop a new polyethylene glycol (PEG) ylated β-elemene
liposome (PEG-Lipo-β-E) and evaluate its characterization, pharmacokinetics, antitumor …
liposome (PEG-Lipo-β-E) and evaluate its characterization, pharmacokinetics, antitumor …
Achieving endo/lysosomal escape using smart nanosystems for efficient cellular delivery
The delivery of therapeutic agents faces significant hurdles posed by the endo-lysosomal
pathway, a bottleneck that hampers clinical effectiveness. This comprehensive review …
pathway, a bottleneck that hampers clinical effectiveness. This comprehensive review …
Engineered EV-mimetic nanoparticles as therapeutic delivery vehicles for high-grade serous ovarian cancer
Simple Summary In this review, we begin with the role of natural extracellular vesicles (EVs)
in high-grade serous ovarian cancer (HGSOC). Then, we narrow our focus on the …
in high-grade serous ovarian cancer (HGSOC). Then, we narrow our focus on the …
Inhaled indomethacin-loaded liposomes as potential therapeutics against non-small cell lung cancer (NSCLC)
Most lung cancer instances are non-small cell lung cancers (NSCLC). As stated by recent
literature, cycloxygenase-2 (COX-2) is upregulated in lung adenocarcinomas. COX-2 relates …
literature, cycloxygenase-2 (COX-2) is upregulated in lung adenocarcinomas. COX-2 relates …
[HTML][HTML] Liposomes co-encapsulating doxorubicin and glucoevatromonoside derivative induce synergic cytotoxic response against breast cancer cell lines
MVM Novais, ER Gomes, MC Miranda, JO Silva… - Biomedicine & …, 2021 - Elsevier
Cancer is one of the main causes of death in the world and thus a global public health
problem. Among the treatments available for cancer are surgery, radiotherapy, and …
problem. Among the treatments available for cancer are surgery, radiotherapy, and …