Runs of homozygosity: current knowledge and applications in livestock
E Peripolli, DP Munari, M Silva, ALF Lima… - Animal …, 2017 - Wiley Online Library
This review presents a broader approach to the implementation and study of runs of
homozygosity (ROH) in animal populations, focusing on identifying and characterizing ROH …
homozygosity (ROH) in animal populations, focusing on identifying and characterizing ROH …
Inbreeding depression in livestock species: review and meta‐analysis
G Leroy - Animal genetics, 2014 - Wiley Online Library
Inbreeding, by virtue of its consequence on traits of interest, is a topic of major interest for
geneticists and animal breeders. Based on meta‐analysis conducted on 57 studies and …
geneticists and animal breeders. Based on meta‐analysis conducted on 57 studies and …
How to study runs of homozygosity using PLINK? A guide for analyzing medium density SNP data in livestock and pet species
R Meyermans, W Gorssen, N Buys, S Janssens - BMC genomics, 2020 - Springer
Background PLINK is probably the most used program for analyzing SNP genotypes and
runs of homozygosity (ROH), both in human and in animal populations. The last decade …
runs of homozygosity (ROH), both in human and in animal populations. The last decade …
Inbreeding depression due to recent and ancient inbreeding in Dutch Holstein–Friesian dairy cattle
Background Inbreeding decreases animal performance (inbreeding depression), but not all
inbreeding is expected to be equally harmful. Recent inbreeding is expected to be more …
inbreeding is expected to be equally harmful. Recent inbreeding is expected to be more …
Inbreeding and runs of homozygosity: A possible solution to an old problem
Quantifying human, plant and livestock inbreeding has been an important goal of
evolutionary biologists and agricultural scientists for nearly a century, and methods to do so …
evolutionary biologists and agricultural scientists for nearly a century, and methods to do so …
Analysis of runs of homozygosity and their relationship with inbreeding in five cattle breeds farmed in Italy
Increased inbreeding is an inevitable consequence of selection in livestock populations. The
analysis of high‐density single nucleotide polymorphisms (SNPs) facilitates the identification …
analysis of high‐density single nucleotide polymorphisms (SNPs) facilitates the identification …
Inbreeding and runs of homozygosity before and after genomic selection in North American Holstein cattle
Background While autozygosity as a consequence of selection is well understood, there is
limited information on the ability of different methods to measure true inbreeding. In the …
limited information on the ability of different methods to measure true inbreeding. In the …
Identification of genomic regions associated with inbreeding depression in Holstein and Jersey dairy cattle
Background Inbreeding reduces the fitness of individuals by increasing the frequency of
homozygous deleterious recessive alleles. Some insight into the genetic architecture of …
homozygous deleterious recessive alleles. Some insight into the genetic architecture of …
A publicly available repository of ROH islands reveals signatures of selection in different livestock and pet species
W Gorssen, R Meyermans, S Janssens… - Genetics Selection …, 2021 - Springer
Background Runs of homozygosity (ROH) have become the state-of-the-art method for
analysis of inbreeding in animal populations. Moreover, ROH are suited to detect signatures …
analysis of inbreeding in animal populations. Moreover, ROH are suited to detect signatures …
Estimation of inbreeding using pedigree, 50k SNP chip genotypes and full sequence data in three cattle breeds
Background Levels of inbreeding in cattle populations have increased in the past due to the
use of a limited number of bulls for artificial insemination. High levels of inbreeding lead to …
use of a limited number of bulls for artificial insemination. High levels of inbreeding lead to …