Megacities are intricate systems that struggle with difficulties including overcrowding, subpar
urban design and planning, inadequate mobility and public transportation, subpar …

The inherent complexity of biomedical systems is well recognized; they are multi-scale, multi-
science systems, bridging a wide range of temporal and spatial scales. This article reviews …

Inherently complex problems from many scientific disciplines require a multiscale modeling
approach. Yet its practical contents remain unclear and inconsistent. Moreover, multiscale …

Neointimal hyperplasia, a process of smooth muscle cell re-growth, is the result of a natural
wound healing response of the injured artery after stent deployment. Excessive neointimal …

In-stent restenosis, the maladaptive response of a blood vessel to injury caused by the
deployment of a stent, is a multiscale system involving a large number of biological and …

Following a review of multiscale simulation methodology, and previous examples of
multiscale models from food science, we present our multiscale simulation framework MULTI …

Recent multiscale applications require more and more often the coupling of many sub-
models, usually originating form different fields of science. Therefore, it is increasingly …

In this paper, we report on the experimental results of running a large, tightly coupled,
distributed multiscale computation over a hybrid High Performance Computing (HPC) …

In this paper we perform a multiscale analysis of the food structuring process of the
expansion of starchy snack foods like keropok, which obtains a solid foam structure. In …

Cellular Automata (CA) are generally acknowledged to be a powerful way to describe and
model natural phenomena [1–3]. There are even tempting claims that nature itself is one big …