Significance of miRNAs on the thyroid cancer progression and resistance to treatment with special attention to the role of cross-talk between signaling pathways

AS Doghish, HA El-Mahdy, A Ismail, M Hegazy… - … -Research and Practice, 2023 - Elsevier
Thyroid cancer (TC) is the most prevalent endocrine malignant tumor. It has many types, the
Papillary thyroid cancer (PTC)(most common and follicular thyroid carcinoma (FTC). Several …

[HTML][HTML] Molecular markers guiding thyroid cancer management

C Nylén, R Mechera, I Maréchal-Ross, V Tsang… - Cancers, 2020 - mdpi.com
The incidence of thyroid cancer is rapidly increasing, mostly due to the overdiagnosis and
overtreatment of differentiated thyroid cancer (TC). The increasing use of potent preclinical …

A retrospective evaluation of the diagnostic performance of an interdependent pairwise MicroRNA expression analysis with a mutation panel in indeterminate thyroid …

SD Finkelstein, JW Sistrunk, C Malchoff, DV Thompson… - Thyroid, 2022 - liebertpub.com
Background: The addition of genetic analysis to the evaluation of thyroid nodule fine-needle
aspiration biopsy samples improves diagnostic accuracy of cytologically indeterminate …

[HTML][HTML] Molecular genetics of follicular-derived thyroid cancer

E Macerola, AM Poma, P Vignali, A Basolo, C Ugolini… - Cancers, 2021 - mdpi.com
Simple Summary Thyroid tumors that derive from follicular cells are not a homogeneous
entity, showing variable morphological appearance and different degrees of differentiation …

[HTML][HTML] Opportunities and challenges of liquid biopsy in thyroid cancer

C Romano, F Martorana, MS Pennisi, S Stella… - International journal of …, 2021 - mdpi.com
Thyroid cancer is the most common malignancy of the endocrine system, encompassing
different entities with distinct histological features and clinical behavior. The diagnostic …

Clinical use of molecular data in thyroid nodules and cancer

AS Alzahrani - The Journal of Clinical Endocrinology & …, 2023 - academic.oup.com
Over the past 3 decades, advances in the molecular genetics of thyroid cancer (TC) have
been translated into diagnostic tests, prognostic markers, and therapeutic agents. The main …

Effect of non-enzymatic glycosylation in the epigenetics of cancer

S Rehman, M Aatif, Z Rafi, MY Khan, U Shahab… - Seminars in Cancer …, 2022 - Elsevier
The non-enzymatic glycosylation or non-enzymatic covalent modifications (NECMs) or
glycation of cellular proteins result in the generation and accumulation of advanced …

Resistance to RET targeted therapy in Thyroid Cancer: Molecular basis and overcoming strategies

M San Roman-Gil, J Pozas, D Rosero-Rodriguez… - Cancer treatment …, 2022 - Elsevier
Thyroid cancer is the most frequently diagnosed endocrine malignancy, with an increasing
incidence over the last decades. The recent advances in understanding the molecular …

CRISPR/Cas mediated epigenome editing for cancer therapy

I Ansari, A Chaturvedi, D Chitkara, S Singh - Seminars in Cancer Biology, 2022 - Elsevier
The understanding of the relationship between epigenetic alterations, their effects on gene
expression and the knowledge that these epigenetic alterations are reversible, have opened …

[HTML][HTML] A comprehensive review on miR-153: mechanistic and controversial roles of miR-153 in tumorigenicity of cancer cells

S Yousefnia - Frontiers in Oncology, 2022 - frontiersin.org
miRNAs play a crucial role in regulating genes involved in cancer progression. Recently,
miR-153 has been mainly well-known as a tumor suppressive miRNA modulating genes in …