From Infection to Immunity: Understanding the Response to SARS-CoV2 Through In-Silico Modeling
Background Immune system conditions of the patient is a key factor in COVID-19 infection
survival. A growing number of studies have focused on immunological determinants to …
survival. A growing number of studies have focused on immunological determinants to …
Intracellular life cycle kinetics of SARS-CoV-2 predicted using mathematical modelling
D Grebennikov, E Kholodareva, I Sazonov… - Viruses, 2021 - mdpi.com
SARS-CoV-2 infection represents a global threat to human health. Various approaches were
employed to reveal the pathogenetic mechanisms of COVID-19. Mathematical and …
employed to reveal the pathogenetic mechanisms of COVID-19. Mathematical and …
Differential kinetics of splenic CD169+ macrophage death is one underlying cause of virus infection fate regulation
V Casella, E Domenjo-Vila, A Esteve-Codina… - Cell Death & …, 2023 - nature.com
Acute infection and chronic infection are the two most common fates of pathogenic virus
infections. While several factors that contribute to these fates are described, the critical …
infections. While several factors that contribute to these fates are described, the critical …
Baicalin mitigates nephropathogenic infectious bronchitis virus infection-induced spleen injury via modulation of mitophagy and macrophage polarization in Hy-Line …
G Tian, C Huang, Z Li, Z Lu, C Feng, Y Zhuang… - Veterinary …, 2023 - Elsevier
Nephropathogenic infectious bronchitis virus (NIBV) infections continue to pose a significant
hazard in the poultry industry. Baicalin is a natural flavonoid that has been reported to have …
hazard in the poultry industry. Baicalin is a natural flavonoid that has been reported to have …
Sensitivity of SARS-CoV-2 life cycle to IFN effects and ACE2 binding unveiled with a stochastic model
Mathematical modelling of infection processes in cells is of fundamental interest. It helps to
understand the SARS-CoV-2 dynamics in detail and can be useful to define the vulnerability …
understand the SARS-CoV-2 dynamics in detail and can be useful to define the vulnerability …
A multiscale model suggests that a moderately weak inhibition of SARS-CoV-2 replication by type I IFN could accelerate the clearance of the virus
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly transmissible
RNA virus that emerged in China at the end of 2019 and caused a large global outbreak …
RNA virus that emerged in China at the end of 2019 and caused a large global outbreak …
[PDF][PDF] Intracellular Life Cycle Kinetics of SARS-CoV-2 Predicted Using Mathematical Modelling. Viruses 2021, 13, 1735
D Grebennikov, E Kholodareva, I Sazonov… - 2021 - academia.edu
SARS-CoV-2 infection represents a global threat to human health. Various approaches were
employed to reveal the pathogenetic mechanisms of COVID-19. Mathematical and …
employed to reveal the pathogenetic mechanisms of COVID-19. Mathematical and …
[PDF][PDF] Mathematical modelling of antiviral immune responses to SARS-CoV-2 infection
G Bocharov, D Grebennikov… - Bioinformatics of Genome …, 2022 - scholar.archive.org
Results: The sensitivity of coronavirus disease severity to the dose of infection and the virus
growth rate, and the limits of protection provided by the type I interferon (IFN) system that …
growth rate, and the limits of protection provided by the type I interferon (IFN) system that …
[PDF][PDF] Multiscale modelling of the structure, regulation and dynamics of immune responses to virus infections
The course and outcome of publicly relevant human infections depend on the immune
system. It functions as an hierarchically organized, spatially structured and pleiotropically …
system. It functions as an hierarchically organized, spatially structured and pleiotropically …