In the last three decades, ablation of atrial fibrillation (AF) has become an evidence-based
safe and efficacious treatment for managing the most common cardiac arrhythmia. In 2007 …

Background: The limited effectiveness of endocardial catheter ablation (CA) for persistent
and long-standing persistent atrial fibrillation (AF) treatment led to the development of a …

Background Ablation of cardiac tissue is an essential tool for the treatment of arrhythmias,
particularly of atrial fibrillation, atrial flutter, and ventricular tachycardia. Current ablation …

Objective Newly published guidelines made the highest level recommendation for surgical
treatment for atrial fibrillation. However, the number of patients without a mitral valve …

Importance Bayesian adaptive trial design has the potential to create more efficient clinical
trials. However, a barrier to the uptake of bayesian adaptive designs for confirmatory trials is …

Background Favorable clinical outcomes are difficult to achieve in long-standing persistent
atrial fibrillation (LSPAF) with catheter ablation (CA). The CONVERGE (Convergence of …

Objective: Expert consensus guidelines recommend surgical ablation (SA) for patients with
symptomatic atrial fibrillation (AF), but less than half of patients with AF undergoing cardiac …

Background Benefits of concomitant atrial fibrillation (AF) surgical treatment are well
established. Cardiac societies support treating AF during cardiac surgery with a class I …

Objectives Concomitant atrial fibrillation often goes untreated because of surgeon concerns
regarding lesion set complexity and pump times. We describe a new cryoablation procedure …

Background Bipolar radiofrequency (RF) clamps are commonly used during surgical
ablation for atrial fibrillation (AF). This study examined the efficacy of an irrigated bipolar RF …