Are we meeting the promise of endotypes and precision medicine in asthma?
While the term asthma has long been known to describe heterogeneous groupings of
patients, only recently have data evolved which enable a molecular understanding of the …
patients, only recently have data evolved which enable a molecular understanding of the …
New perspectives in the diagnosis and management of allergic fungal airway disease
AJ Wardlaw, EM Rick, L Pur Ozyigit… - Journal of Asthma …, 2021 - Taylor & Francis
Allergy to airway-colonising, thermotolerant, filamentous fungi represents a distinct
eosinophilic endotype of often severe lung disease. This endotype, which particularly affects …
eosinophilic endotype of often severe lung disease. This endotype, which particularly affects …
Attenuation of ovalbumin-induced inflammation and lung oxidative injury in asthmatic rats by Zingiber officinale extract: combined in silico and in vivo study on antioxidant …
O Jedli, H Ben-Nasr, N Zammel, T Rebai, M Saoudi… - 3 Biotech, 2022 - Springer
In the present study we focused on the anti-asthmatic and antioxidant effects of Zingiber
officinalis roscoe L.(ZO) aqueous extract. This study includes 20 adult male rats, which were …
officinalis roscoe L.(ZO) aqueous extract. This study includes 20 adult male rats, which were …
[HTML][HTML] Airway microbiota in children with bronchial mucus plugs caused by Mycoplasma pneumoniae pneumonia
X Xu, L Wu, Y Sheng, J Liu, Z Xu, W Kong, L Tang… - Respiratory …, 2020 - Elsevier
Background There is increasing evidence for a role of lung microbiota in the pathogenesis of
Mycoplasma pneumoniae pneumonia (MPP). However, the alterations of lung microbiota in …
Mycoplasma pneumoniae pneumonia (MPP). However, the alterations of lung microbiota in …
Update on the Role of Fungus in Allergy, Asthma, and the Unified Airway
BH Cameron, SW Gong, DB Corry… - … Clinics of North …, 2023 - oto.theclinics.com
The unified airway refers to the combined upper and lower airways and their shared
pathophysiologic relationships. These 2 systems are thought to be interconnected, and …
pathophysiologic relationships. These 2 systems are thought to be interconnected, and …
[HTML][HTML] Pulmonary Mycosis Drives Forkhead Box Protein A2 Degradation and Mucus Hypersecretion Through Activation of the Spleen Tyrosine Kinase–Epidermal …
Pulmonary mycoses are difficult to treat and detrimental to patients. Fungal infections
modulate the lung immune response, induce goblet cell hyperplasia and metaplasia, and …
modulate the lung immune response, induce goblet cell hyperplasia and metaplasia, and …
Airway mucus, infection, and therapeutic strategies
M NandyMazumdar - Viral, Parasitic, Bacterial, and Fungal Infections, 2023 - Elsevier
The respiratory tract epithelium is hydrated by a mucous layer, which forms a protective
barrier for the defense against sometimes life-threatening foreign particles, including …
barrier for the defense against sometimes life-threatening foreign particles, including …
[HTML][HTML] Humoral first-line mucosal innate defence in vivo
C Persson - Journal of Innate Immunity, 2020 - karger.com
Based on observations in vivo in guinea-pig and human airways, this review presents
plasma exudation as non-sieved transmission of bulk plasma across an unperturbed …
plasma exudation as non-sieved transmission of bulk plasma across an unperturbed …
The Role of the Microbiome in Asthma Inception and Phenotype
SR White, YJ Huang - The Microbiome in Respiratory Disease: Principles …, 2022 - Springer
The lung microbiome in adult asthma is the product of a long period of dynamic shaping by
microorganisms and the host from infancy onwards. The use of next-generation sequencing …
microorganisms and the host from infancy onwards. The use of next-generation sequencing …
[HTML][HTML] Chair's summary: secreted mucins in lung diseases
BF Dickey - Annals of the American Thoracic Society, 2018 - atsjournals.org
The 33rd Transatlantic Airway Conference was held January 17–19, 2018, in Lucerne,
Switzerland. The topic of this year's conference was the protective and pathologic roles of …
Switzerland. The topic of this year's conference was the protective and pathologic roles of …