Orexins and Prostate Cancer: State of the Art and Potential Experimental and Therapeutic Perspectives

A Costagliola, R Lombardi, G Liguori… - Cancer Genomics & …, 2023 - cgp.iiarjournals.org
Prostate cancer (PCa) is the second most common cancer in humans. Peptides have
recently been used as targeted therapeutics in cancers, due to their extensive multi …

Xanthatin suppresses pancreatic cancer cell growth via the ROS/RBL1 signaling pathway: In vitro and in vivo insights

Y Geng, P Liu, Y Xie, Y Liu, X Zhang, X Hou, L Zhang - Phytomedicine, 2023 - Elsevier
Background As a malignant digestive system tumor, pancreatic cancer has a high mortality
rate. Xanthatin is a sesquiterpene lactone monomer compound purified from the traditional …

[HTML][HTML] Capsaicin Exerts Antitumor Activity in Mesothelioma Cells

E Andretta, A Costa, E Ventura, M Quintiliani… - Nutrients, 2024 - mdpi.com
Background/Objectives: Mesothelioma is an aggressive cancer with limited treatment
options. Mesothelioma therapy often involves a multimodal approach including surgery …

Progranulin and EGFR modulate receptor-like tyrosine kinase sorting and stability in mesothelioma cells

E Ventura, A Belfiore, RV Iozzo… - … of Physiology-Cell …, 2023 - journals.physiology.org
Progranulin is a growth factor with pro-tumorigenic activity. We recently demonstrated that in
mesothelioma, progranulin regulates cell migration, invasion, adhesion, and in vivo tumor …

Complexity of progranulin mechanisms of action in mesothelioma

E Ventura, C Xie, S Buraschi, A Belfiore… - Journal of Experimental …, 2022 - Springer
Background Mesothelioma is an aggressive disease with limited therapeutic options. The
growth factor progranulin plays a critical role in several cancer models, where it regulates …

A new TGF‐β risk score predicts clinical and immune landscape in colorectal cancer patients

B Tang, B Liu, Z Zeng - Annals of Gastroenterological Surgery, 2024 - Wiley Online Library
Background Aberrant TGF‐β signaling pathway can lead to invasive phenotype of colorectal
cancer (CRC), resulting in poor prognosis. It is pivotal to develop an effective prognostic …

[HTML][HTML] 磷酸化蛋白质组学联合蛋白质组学分析敲除维甲酸诱导蛋白16 对人结肠癌细胞的影响

陈奕孛, 苗根, 王文, 丁翠玲, 戚中田 - 肿瘤防治研究, 2024 - zlfzyj.com
磷酸化蛋白质组学联合蛋白质组学分析敲除维甲酸诱导蛋白16对人结肠癌细胞的影响 高级搜索
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[HTML][HTML] The somatic mutational landscape and role of the ARID1A gene in hepatocellular carcinoma

GX Meng, CC Yang, LJ Yan, YF Yang, YC Yan… - Heliyon, 2023 - cell.com
Introduction Hepatocellular carcinoma (HCC) is one of the most common malignant tumours
worldwide. Clarification of the somatic mutational landscape of important genes could reveal …

Proteomics and Phosphoproteomics Analysis of Effect of Retinoic Acid-Induced Protein 16 Knockout on Human Colon Cancer Cells

C Yibo, M Gen, D Cuiling, QI Zhongtian - Cancer Research on Prevention …, 2024 - zlfzyj.com
Objective To analyze the differences in the expressions of the total and phosphorylated
proteins in human colon cancer HCT116 cells after the knockout (KO) of retinoic acid …

The multifaceted role of PRELP in the regulation of retinoblastoma progression

JD Hopkins - 2023 - discovery.ucl.ac.uk
Small leucine-rich proteoglycans are secreted proteins that organise extracellular matrices
and stipulate appropriate cellular signalling to maintain tissue homeostasis. Loss of these …