The Omicron variant continuously evolves under the humoral immune pressure exerted by
vaccination and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection …

The generation of efficient fluid flow is crucial for organismal development and homeostasis,
sexual reproduction, and motility. Multi‐ciliated cells possess fields of motile cilia that beat in …

Ciliated epithelia are widespread in animals and play crucial roles in many developmental
and physiological processes. Epithelia composed of multi-ciliated cells allow for directional …

Heterotrimeric G proteins (Gαβγ) are molecular switches that relay signals from 7-
transmembrane receptors located at the cell surface to the cytoplasm. The function of these …

Mucociliary clearance, which is conducted by beating cilia cooperating with the surface
mucous layer, is a major host defense mechanism of the airway epithelium. Ezrin, a …

Rho GTPases are essential regulators of the actin cytoskeleton. They are involved in various
physiological and biochemical processes such as the regulation of cytoskeleton dynamics …

For mucociliary clearance of pathogens, tracheal multiciliated epithelial cells (MCCs)
organize coordinated beating of cilia, which originate from basal bodies (BBs) with basal …

Wnt signaling pathways represent an evolutionarily highly conserved, intricate network of
molecular interactions that regulates various aspects of cellular behavior, including …

Multiple motile cilia are formed at the apical surface of multi-ciliated cells in the epithelium of
the oviduct or the fallopian tube, the trachea, and the ventricle of the brain. Those cilia beat …

Establishment of apicobasal polarity and the organization of the cytoskeleton must operate
coordinately to ensure proper epithelial cell shape and function. However, the precise …