Exosomes

DM Pegtel, SJ Gould - Annual review of biochemistry, 2019 - annualreviews.org
Exosomes are small, single-membrane, secreted organelles of∼ 30 to∼ 200 nm in
diameter that have the same topology as the cell and are enriched in selected proteins …

Role of exosomal proteins in cancer diagnosis

W Li, C Li, T Zhou, X Liu, X Liu, X Li, D Chen - Molecular cancer, 2017 - Springer
Exosomes are emerging as a new type of cancer biomarkers. Exosome is a bilayered nano-
sized vesicle secreted by various living cells in all body fluids. Based on the expanding …

RAB31 marks and controls an ESCRT-independent exosome pathway

D Wei, W Zhan, Y Gao, L Huang, R Gong, W Wang… - Cell research, 2021 - nature.com
Exosomes are generated within the multivesicular endosomes (MVEs) as intraluminal
vesicles (ILVs) and secreted during the fusion of MVEs with the cell membrane. The …

Role of exosomes in prostate cancer metastasis

T Akoto, S Saini - International journal of molecular sciences, 2021 - mdpi.com
Prostate cancer remains a life-threatening disease among men worldwide. The majority of
PCa-related mortality results from metastatic disease that is characterized by metastasis of …

Exosomes in tumor microenvironment: novel transporters and biomarkers

Z Wang, JQ Chen, JL Liu, L Tian - Journal of translational medicine, 2016 - Springer
Tumor microenvironment (TME) plays an integral part in the biology of cancer, participating
in tumor initiation, progression, and response to therapy. Exosome is an important part of …

Exosomes, new biomarkers in early cancer detection

SH Jalalian, M Ramezani, SA Jalalian, K Abnous… - Analytical …, 2019 - Elsevier
Exosomes are endosomal-derived vesicles, playing a major role in cell-to-cell
communication. Multiple cells secret these vesicles to induce and inhibit different cellular …

Tumor‐derived exosomes: Implication in angiogenesis and antiangiogenesis cancer therapy

C Aslan, S Maralbashi, F Salari… - Journal of cellular …, 2019 - Wiley Online Library
Tumor cells utilize different strategies to communicate with neighboring tissues for facilitating
tumor progression and invasion, one of these strategies has been shown to be the release …

Simultaneous multiplexed detection of exosomal microRNAs and surface proteins for prostate cancer diagnosis

S Cho, HC Yang, WJ Rhee - Biosensors and Bioelectronics, 2019 - Elsevier
Since the tumor is extremely heterogeneous, a single biomarker cannot reflect the exact
symptoms of the disease or its stage. Exosomes are biomarker reservoirs that provide …

Ceramide and exosomes: a novel target in cancer biology and therapy

A Elsherbini, E Bieberich - Advances in Cancer Research, 2018 - Elsevier
Exosomes are secreted extracellular vesicles (EVs) that carry micro RNAs and other factors
to reprogram cancer cells and tissues affected by cancer. Exosomes are exchanged …

Exosomes and cancer: from molecular mechanisms to clinical applications

A Jafari, A Babajani, M Abdollahpour-Alitappeh… - Medical Oncology, 2021 - Springer
Exosomes are extracellular nanovesicles secreted from almost all types of normal and
cancer cells. Collective evidence suggests that exosomes participate in cell–cell …