Platinum‐containing chemotherapy agents (cisplatin, carboplatin, oxaliplatin) have been
approved in the first‐line setting of numerous malignancies, such as ovarian, bladder, head …

Pancreatic cancer (PC) is a leading cause of cancer related deaths in United States. The
lack of early symptoms results in latestage detection and a high mortality rate. Currently, the …

Advanced pancreatic adenocarcinoma historically has a poor prognosis and the mortality
rate has remained unchanged for over a decade. Common treatment options for patients …

Background: Studies document that magnesium is inversely associated with the risk of
diabetes, which is a risk factor of pancreatic cancer. However, studies on the direct …

Since its first description Focal Adhesion Kinase (FAK), a cytoplasmatic tyrosine kinase, has
been implicated in the formation and progression of solid and liquid malignant tumors …

Pancreatic ductal adenocarcinoma (PDAC) represents permanent and ever rising issue
worldwide. Five-year survival does not exceed 3 to 6%, ie the worst result among solid …

One major barrier in the development of pancreas cancer therapeutics is the selective
delivery of the drugs to their cellular targets. We have previously developed several sigma-2 …

Возрастающая дистанция между практическим здравоохранением и накапливающейся
теоретической информацией в области биомедицинских исследований диктует …

Pancreas cancer is the fourth leading cause of cancer death due to the limited treatment
success rate. The wide number of signalling pathway aberrations contributing to …

Organisms constantly undergo various stresses within their life span, which can damage
their DNA. In order to maintain genomic stability and counteract the development of …