Thymoquinone and its therapeutic potentials

S Darakhshan, AB Pour, AH Colagar… - Pharmacological …, 2015 - Elsevier
Herbal medicine has attracted great attention in the recent years and is increasingly used as
alternatives to chemical drugs. Several lines of evidence support the positive impact of …

Therapeutic potential and pharmaceutical development of thymoquinone: a multitargeted molecule of natural origin

SN Goyal, CP Prajapati, PR Gore, CR Patil… - Frontiers in …, 2017 - frontiersin.org
Thymoquinone, a monoterpene molecule is chemically known as 2-methyl-5-isopropyl-1, 4-
benzoquinone. It is abundantly present in seeds of Nigella sativa L. that is popularly known …

Moroccan antidiabetic medicinal plants: Ethnobotanical studies, phytochemical bioactive compounds, preclinical investigations, toxicological validations and clinical …

A Bouyahya, N El Omari, N Elmenyiy… - Trends in Food Science …, 2021 - Elsevier
Background Moroccan flora is rich with medicinal plants that are widely used in traditional
medicine for the treatment of various diseases including diabetes. These plants possess …

Effects of Nigella sativa and thymoquinone on biochemical and subcellular changes in pancreatic β‐cells of streptozotocin‐induced diabetic rats

NE Abdelmeguid, R Fakhoury, SM Kamal… - Journal of …, 2010 - Wiley Online Library
Background: The present study investigated the effects of Nigella sativa aqueous extract and
oil, as well as thymoquinone, on serum insulin and glucose concentrations in streptozotocin …

[HTML][HTML] Anti-inflammatory effects of thymoquinone and its protective effects against several diseases

Z Kohandel, T Farkhondeh, M Aschner… - Biomedicine & …, 2021 - Elsevier
Abstract Thymoquinone (TQ, 2-methyl-5-isopropyl-1, 4-benzoquinone), a monoterpene
molecule present in Nigella sativa L., has an anti-inflammatory, anti-oxidant, and anti …

Beneficial effects of thymoquinone on hepatic key enzymes in streptozotocin–nicotinamide induced diabetic rats

L Pari, C Sankaranarayanan - Life sciences, 2009 - Elsevier
AIMS: The present study was designed to evaluate the antihyperglycemic potential of
thymoquinone (TQ), major constituent of Nigella sativa seeds on the activities of key …

Nigella sativa L. and Its Active Compound Thymoquinone in the Clinical Management of Diabetes: A Systematic Review

MF Mahomoodally, MZ Aumeeruddy… - International journal of …, 2022 - mdpi.com
Despite existing conventional hypoglycemic drugs to manage diabetes, their non-availability
and cost in low-income countries coupled with the associated side effects remain a major …

Improvement of antihyperglycemic activity of nano-thymoquinone in rat model of type-2 diabetes

R Rani, S Dahiya, D Dhingra, N Dilbaghi… - Chemico-biological …, 2018 - Elsevier
Thymoquinone is a bioactive constituent of Nigella sativa seeds. It has been reported to
possess antihyperglycemic effect in rats. However, the effect of nanoformulation (NF) of …

Thymoquinone: a review on its pharmacological importance, and its association with oxidative stress, COVID-19, and radiotherapy

S Taysi, FS Algburi, ZR Mohammed… - Mini Reviews in …, 2022 - ingentaconnect.com
Widely consumed worldwide, Nigella sativa (NS) is a medicinal herb commonly used in
various alternative medicine systems, such as Unani and Tibb, Ayurveda, and Siddha …

Antidiabetic properties of a spice plant Nigella sativa

ML Mathur, J Gaur, R Sharma, KR Haldiya - Journal of Endocrinology and …, 2011 - jofem.org
Seeds of Nigella sativa (black cumin/kalonji) used in pickles as spice, have also been
traditionally used in treatment of many diseases including diabetes and hypertension …