Molecular and evolutionary processes generating variation in gene expression

MS Hill, P Vande Zande, PJ Wittkopp - Nature Reviews Genetics, 2021 - nature.com
Heritable variation in gene expression is common within and between species. This
variation arises from mutations that alter the form or function of molecular gene regulatory …

A multi-tissue atlas of regulatory variants in cattle

S Liu, Y Gao, O Canela-Xandri, S Wang, Y Yu, W Cai… - Nature …, 2022 - nature.com
Abstract Characterization of genetic regulatory variants acting on livestock gene expression
is essential for interpreting the molecular mechanisms underlying traits of economic value …

The application of omics in ruminant production: A review in the tropical and sub-tropical animal production context

DM Ribeiro, AAK Salama, ACM Vitor, A Argüello… - Journal of …, 2020 - Elsevier
The demand for animal products (eg dairy and beef) in tropical regions is expected to
increase in parallel with the public demand for sustainable practices, due to factors such as …

[HTML][HTML] Improved annotation of the domestic pig genome through integration of Iso-Seq and RNA-seq data

H Beiki, H Liu, J Huang, N Manchanda, D Nonneman… - BMC genomics, 2019 - Springer
Background Our understanding of the pig transcriptome is limited. RNA transcript diversity
among nine tissues was assessed using poly (A) selected single-molecule long-read …

[HTML][HTML] Identification of genomic regions and candidate genes associated with body weight and body conformation traits in Karachai goats

AA Easa, M Selionova, M Aibazov, T Mamontova… - Genes, 2022 - mdpi.com
The objective of this study was to identify the SNPs and candidate genes related to body
weight and seven body conformation traits at the age of 8 months in the Russian aboriginal …

[HTML][HTML] Functional annotation of the cattle genome through systematic discovery and characterization of chromatin states and butyrate-induced variations

L Fang, S Liu, M Liu, X Kang, S Lin, B Li, EE Connor… - BMC biology, 2019 - Springer
Background The functional annotation of genomes, including chromatin accessibility and
modifications, is important for understanding and effectively utilizing the increased amount of …

Genome-wide mapping of regulatory variants for temperature-and salinity-adaptive genes reveals genetic basis of genotype-by-environment interaction in …

K Zhang, Q Yang, M Du, Z Zhang, W Wang… - Environmental …, 2023 - Elsevier
Regulatory variants in gene expression serve as bridges linking genetic variation and
phenotypic plasticity. Environmental conditions typically influence the effects of regulatory …

A comprehensive catalogue of regulatory variants in the cattle transcriptome

S Liu, Y Gao, O Canela-Xandri, S Wang, Y Yu, W Cai… - BioRxiv, 2020 - biorxiv.org
Abstract Characterization of genetic regulatory variants acting on the transcriptome of
livestock is essential for interpreting the molecular mechanisms underlying traits of …

[HTML][HTML] Potential biomarkers for feed efficiency-related traits in nelore cattle identified by co-expression network and integrative genomics analyses

AO De Lima, JE Koltes, WJS Diniz… - Frontiers in …, 2020 - frontiersin.org
Feed efficiency helps to reduce environmental impacts from livestock production, improving
beef cattle profitability. We identified potential biomarkers (hub genes) for feed efficiency, by …

[HTML][HTML] Novel putative causal mutations associated with fat traits in Nellore cattle uncovered by eQTLs located in open chromatin regions

IS Garcia, B Silva-Vignato, ASM Cesar, J Petrini… - Scientific Reports, 2024 - nature.com
Intramuscular fat (IMF) and backfat thickness (BFT) are critical economic traits impacting
meat quality. However, the genetic variants controlling these traits need to be better …