Type 2 diabetes and its impact on the immune system

A Berbudi, N Rahmadika, AI Tjahjadi… - Current diabetes …, 2020 - ingentaconnect.com
Introduction: Type 2 Diabetes (T2D) is a major health problem worldwide. This metabolic
disease is indicated by high blood glucose levels due to insufficient insulin production by the …

Diabetes and infection: assessing the association with glycaemic control in population-based studies

J Pearson-Stuttard, S Blundell, T Harris… - The lancet Diabetes & …, 2016 - thelancet.com
Diabetes is a leading cause of morbidity and mortality. The global burden of diabetes is
rising because of increased obesity and population ageing. Although preventive and …

Wound chronicity, impaired immunity and infection in diabetic patients

N Rodríguez-Rodríguez, I Martínez-Jiménez… - MEDICC …, 2022 - SciELO Public Health
BACKGROUND Diabetic foot ulcers are a common diabetic complication leading to
alarming figures of amputation, disability, and early mortality. The diabetic glucooxidative …

Macrophages, low-grade inflammation, insulin resistance and hyperinsulinemia: a mutual ambiguous relationship in the development of metabolic diseases

GP Püschel, J Klauder, J Henkel - Journal of Clinical Medicine, 2022 - mdpi.com
Metabolic derangement with poor glycemic control accompanying overweight and obesity is
associated with chronic low-grade inflammation and hyperinsulinemia. Macrophages, which …

Diabetes and immunity to tuberculosis

N Martinez, H Kornfeld - European journal of immunology, 2014 - Wiley Online Library
The dual burden of tuberculosis (TB) and diabetes has attracted much attention in the past
decade as diabetes prevalence has increased dramatically in countries already afflicted with …

Macrophage dysfunction in the pathogenesis and treatment of asthma

M Fricker, PG Gibson - European Respiratory Journal, 2017 - Eur Respiratory Soc
Asthma is a chronic respiratory condition frequently associated with aberrant airway and
systemic inflammation. Various inflammatory phenotypes in asthmatic airways have been …

Proresolution therapy for the treatment of delayed healing of diabetic wounds

Y Tang, MJ Zhang, J Hellmann, M Kosuri… - Diabetes, 2013 - Am Diabetes Assoc
Obesity and type 2 diabetes are emerging global epidemics associated with chronic, low-
grade inflammation. A characteristic feature of type 2 diabetes is delayed wound healing …

Acquired immunodeficiencies and tuberculosis: focus on HIV/AIDS and diabetes mellitus

K Ronacher, SA Joosten, R van Crevel… - Immunological …, 2015 - Wiley Online Library
The spread of human immunodeficiency virus (HIV) infection within Africa led to marked
increases in numbers of cases of tuberculosis (TB), and although the epidemic peaked in …

Immunomodulatory effects of black seeds and garlic on alloxan-induced diabetes in albino rat

BKA Abel-Salam - Allergologia et immunopathologia, 2012 - Elsevier
Background Alteration in the proliferation capacity of leukocytes and in the level of some
cytokines, such as TNF-α, IL-4 and IL-8 have been suggested to associate with Diabetes …

The importance of metabolism for immune homeostasis in allergic diseases

J Rodriguez-Coira, A Villaseñor, E Izquierdo… - Frontiers in …, 2021 - frontiersin.org
There is increasing evidence that the metabolic status of T cells and macrophages is
associated with severe phenotypes of chronic inflammation, including allergic inflammation …