Dry eye disease (DED) is a frequently observed eye complaint, which has recently attracted
considerable research interest. Conventional therapy for DED involves the use of artificial …

Engineering protein and peptide-based materials for drug delivery applications has gained
momentum due to their biochemical and biophysical properties over synthetic materials …

Elastin-like polypeptides (ELPs) are stimulus-responsive biopolymers derived from human
elastin. Their unique properties—including lower critical solution temperature phase …

The use of recombinant elastin-like materials, or elastin-like recombinamers (ELRs), in drug-
delivery applications is reviewed in this work. Although ELRs were initially used in similar …

New and improved nanomaterials are constantly being developed for biomedical purposes.
Nanomaterials based on elastin-like polypeptides (ELPs) have increasingly shown potential …

Hybrid or recombinant protein-polymers, peptide-based biomaterials, and antibody-targeted
therapeutics are widely explored for various ocular conditions and vision correction. They …

Oxidative stress plays a central role in dry eye disease (DED), which can destroy the mucin
layer on the ocular surface. The currently available eye drops are palliative and short-lived …

Multidisciplinary research efforts in the field of drug delivery have led to the development of
a variety of drug delivery systems (DDS) designed for site-specific delivery of diagnostic and …

Multifunctional nanomaterials are rapidly emerging for ophthalmic delivery of therapeutics to
facilitate safe and effective targeting with improved patient compliance. Because of their …

Cellular secretion depends on exocytosis of secretory vesicles and discharge of vesicle
contents. Actin and myosin are essential for pre-fusion and post-fusion stages of exocytosis …