Turmeric (Curcuma longa) has been used for thousands of years for the prevention and
treatment of various chronic diseases. Curcumin is just one of> 200 ingredients in turmeric …

Background Cytokine storm is the exaggerated immune response often observed in viral
infections. It is also intimately linked with the progression of COVID-19 disease as well as …

Cancer is a prevalent cause of mortality around the world. Aberrated activation of Janus
kinase (JAK)/signal transducer and activator of transcription (STAT) signaling pathway …

Background Chronic diseases are a major cause of mortality worldwide, and despite the
recent development in treatment modalities, synthetic drugs have continued to show toxic …

Spinal cord injury (SCI) is a neurological disorder associated with the loss of sensory and
motor function. Understanding the precise dysregulated signaling pathways, especially …

In spite of billions of dollars expended on cancer research every year, the incidence rate and
the mortality rate due to this widespread disease has increased drastically over the last few …

Sepsis is an organ dysfunction caused by an uncontrolled inflammatory response from the
host to an infection. Sepsis is the main cause of morbidity and mortality in intensive care …

Signal transducer and activator of transcription (STAT) proteins are latent transcription
factors that reside in the cytoplasm of several types of cells. In canonical signaling, upon …

Chalcones are a group of naturally occurring compounds that have biological effects that
include anti-inflammatory, anti-cancer, and antibacterial properties. Current chalcone …

The past few decades have witnessed widespread research to challenge carcinogenesis;
however, it remains one of the most important health concerns with the worst prognosis and …